SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

Markus Hoffmann(German Primate Center), Hannah Kleine‐Weber(German Primate Center), Simon Schroeder(Humboldt-Universität zu Berlin), Nadine Krüger(University of Veterinary Medicine Hannover, Foundation), Tanja Herrler(Berufsgenossenschaftliche Unfallklinik Murnau), Sandra Erichsen(Paracelsus Medical University), Tobias S. Schiergens(Ludwig-Maximilians-Universität München), Georg Herrler(University of Veterinary Medicine Hannover, Foundation), Nai‐Huei Wu(University of Veterinary Medicine Hannover, Foundation), Andreas Nitsche(Robert Koch Institute), Marcel A. Müller(Sechenov University), Christian Drosten(Humboldt-Universität zu Berlin), Stefan Pöhlmann(German Primate Center)
Cell
March 8, 2020
10.1016/j.cell.2020.02.052
Cited by 21,314Open Access
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