[Exploring the mechanism of liver enzyme abnormalities in patients with novel coronavirus-infected pneumonia].

Guiwen Guan; Linbo Gao; Jianwen Wang; Xiajie Wen; Tianhao Mao; Siwen Peng; Ting Zhang; Xiangmei Chen; Fengmin Lu

doi:10.3760/cma.j.issn.1007-3418.2020.02.002

[Exploring the mechanism of liver enzyme abnormalities in patients with novel coronavirus-infected pneumonia].

Guiwen Guan(Peking University), Linbo Gao(Peking University), Jianwen Wang(Peking University), Xiajie Wen(Peking University), Tianhao Mao(Peking University), Siwen Peng(Peking University), Ting Zhang(Peking University), Xiangmei Chen(Peking University), Fengmin Lu(Peking University)

PubMed

February 20, 2020

10.3760/cma.j.issn.1007-3418.2020.02.002

Cited by 179Open Access

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Abstract

We assumed that in addition to the over activated inflammatory response in patients with NCP, the up-regulation of ACE2 expression in liver tissue caused by compensatory proliferation of hepatocytes derived from bile duct epithelial cells may also be the possible mechanism of liver tissue injury caused by 2019 novel coronavirus infection.

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