Advanced maternal age alters expression of maternal effect genes that are essential for human oocyte quality

Jingjing Zhang(Huazhong Agricultural University), Xiaoyan Liu(Yuhuangding Hospital), Li Chen(Huazhong Agricultural University), Shouxin Zhang(Huazhong Agricultural University), Xia Zhang(Huazhong Agricultural University), Cuifang Hao(Yuhuangding Hospital), Yi‐Liang Miao(Huazhong Agricultural University)
Aging
February 25, 2020
Cited by 108Open Access
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Abstract

was a key gene affecting the oocyte quality and early embryo development. These results will contribute new knowledge on the molecular mechanisms of female ovary aging and establish a criterion to evaluate the quality of oocytes in women with advanced maternal age.


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