Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression

Jamie E. Craig(Flinders University), Xikun Han(The University of Queensland), Ayub Qassim(Flinders University), Mark Hassall(Flinders University), Jessica N. Cooke Bailey(Case Western Reserve University), Tyler G. Kinzy(Case Western Reserve University), Anthony P. Khawaja(Moorfields Eye Hospital NHS Foundation Trust), Jiyuan An(QIMR Berghofer Medical Research Institute), Henry Marshall(Flinders University), Puya Gharahkhani(QIMR Berghofer Medical Research Institute), Robert P. Igo(Case Western Reserve University), Stuart L. Graham(Macquarie University), Paul R. Healey(The University of Sydney), Jue‐Sheng Ong(QIMR Berghofer Medical Research Institute), Tiger Zhou(Flinders University), Owen M. Siggs(Flinders University), Matthew H. Law(QIMR Berghofer Medical Research Institute), Emmanuelle Souzeau(Flinders University), Bronwyn Ridge(Flinders University), Pirro G. Hysi(St Thomas' Hospital), Kathryn P. Burdon(University of Tasmania), Richard Mills(Flinders University), John Landers(Flinders University), Jonathan B. Ruddle(The University of Melbourne), Ashish Agar(Prince of Wales Hospital), Anna Galanopoulos(Royal Adelaide Hospital), Andrew White(The University of Sydney), Colin E. Willoughby(Belfast Health and Social Care Trust), Nicholas H. Andrew(Flinders University), Stephen Best(Greenlane Clinical Centre), Andrea L. Vincent(University of Auckland), Ivan Goldberg(The University of Sydney), Graham Radford‐Smith(QIMR Berghofer Medical Research Institute), Nicholas G. Martin(QIMR Berghofer Medical Research Institute), Grant W. Montgomery(The University of Queensland), Véronique Vitart(Institute of Genetics and Cancer), René Hoehn(University of Bern), Robert Wojciechowski(National Institutes of Health), Jost B. Jonas(Heidelberg University), Tin Aung(Singapore National Eye Center), Louis R. Pasquale(Icahn School of Medicine at Mount Sinai), Angela J. Cree(University of Southampton), Sobha Sivaprasad(National Institute for Health Research), Neeru A. Vallabh(University of Liverpool), Ananth C. Viswanathan(Moorfields Eye Hospital NHS Foundation Trust), Francesca Pasutto(Friedrich-Alexander-Universität Erlangen-Nürnberg), Jonathan L. Haines(Case Western Reserve University), Caroline C. W. Klaver(Erasmus MC), Cornelia M. van Duijn(Erasmus MC), Robert J. Casson(The University of Adelaide), Paul J. Foster(Moorfields Eye Hospital NHS Foundation Trust), Peng T. Khaw(Moorfields Eye Hospital NHS Foundation Trust), Christopher J. Hammond(St Thomas' Hospital), David A. Mackey(Lions Eye Institute), Paul Mitchell(The University of Sydney), Andrew Lotery(University of Southampton), Janey L. Wiggs(Massachusetts Eye and Ear Infirmary), Alex W. Hewitt(University of Tasmania), Stuart MacGregor(QIMR Berghofer Medical Research Institute)
Nature Genetics
January 20, 2020
Cited by 352Open Access
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