Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4+ T Cells

Anna Śledzińska(London Cancer), Maria Vila de Mucha(Cancer Research UK), Katharina Bergerhoff(London Cancer), Alastair Hotblack(London Cancer), Dafne Franz Demane(London Cancer), Ehsan Ghorani(London Cancer), Ayse U. Akarca(University College Hospital), Maria A. V. Marzolini(London Cancer), Isabelle Solomon(London Cancer), Frederick Arce Vargas(London Cancer), Martin Pulé(London Cancer), Masahiro Ono(Imperial College London), Benedict Seddon(The Royal Free Hospital), George Kassiotis(The Francis Crick Institute), Charlotte E. Ariyan(Memorial Sloan Kettering Cancer Center), Thomas Korn(TUM Klinikum), Teresa Marafioti(University College Hospital), Graham M. Lord(University of Manchester), Hans J. Stauss(The Royal Free Hospital), Richard G. Jenner(University College London), Karl S. Peggs(Cancer Research UK), Sergio A. Quezada(London Cancer)
Immunity
January 1, 2020
Cited by 225Open Access
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Abstract

T cells and offer a pathway to enhancement of anti-tumor activity through their manipulation.


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