Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein
Enyong Dai(Jilin University), Leng Han(Jilin University), Jiao Liu(Third Affiliated Hospital of Guangzhou Medical University), Yangchun Xie(Central South University), Guido Kroemer(Karolinska University Hospital), Daniel J. Klionsky(University of Michigan), Herbert J. Zeh(Southwestern Medical Center), Rui Kang(Southwestern Medical Center), Jing Wang(Jilin University), Daolin Tang(Third Affiliated Hospital of Guangzhou Medical University)
Cited by 583Open Access
Abstract
DAMP, damage-associated molecular pattern; PBMCMs, peripheral blood mononuclear cell-derived macrophages; PDAC, pancreatic ductal adenocarcinoma; s.c., subcutaneously; TAMs, tumor-associated macrophages; TME, tumor microenvironment.
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