Enhancing Intracellular Accumulation and Target Engagement of PROTACs with Reversible Covalent Chemistry

Wenhao Guo(Baylor College of Medicine), Jin Wang(Baylor College of Medicine)

bioRxiv (Cold Spring Harbor Laboratory)

December 30, 2019

10.1101/2019.12.30.873588

Cited by 20

Related Papers

Enhancing intracellular accumulation and target engagement of PROTACs with reversible covalent chemistry

|Nature Communications|2020|204

Steroid Receptor Coactivator-3 (SRC-3/AIB1) as a Novel Therapeutic Target in Triple Negative Breast Cancer and Its Inhibition with a Phospho-Bufalin Prodrug

|PLoS ONE|2015|38

MCU complex: Exploring emerging targets and mechanisms of mitochondrial physiology and pathology

|Journal of Advanced Research|2024|34

Development of a RIPK1 degrader to enhance antitumor immunity

|Nature Communications|2024|25

COOKIE-Pro: covalent inhibitor binding kinetics profiling on the proteome scale

|Nature Communications|2025|3