Functional Carbon Quantum Dots as Medical Countermeasures to Human Coronavirus
Aleksandra Łoczechin(Centre National de la Recherche Scientifique), Karin Séron(Centre National de la Recherche Scientifique), Alexandre Barras(Centre National de la Recherche Scientifique), Emerson Giovanelli(Centre National de la Recherche Scientifique), Sandrine Belouzard(Centre National de la Recherche Scientifique), Yen‐Ting Chen(Ruhr University Bochum), Nils Metzler‐Nolte(Ruhr University Bochum), Rabah Boukherroub(Centre National de la Recherche Scientifique), Jean Dubuisson(Centre National de la Recherche Scientifique), Sabine Szunerits(Centre National de la Recherche Scientifique)
Cited by 313Open Access
Abstract
. The underlying mechanism of action of these CQDs was revealed to be inhibition of HCoV-229E entry that could be due to interaction of the functional groups of the CQDs with HCoV-229E entry receptors; surprisingly, an equally large inhibition activity was observed at the viral replication step.
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