Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures

John А. Kanis(Australian Catholic University), Nicholas C. Harvey(MRC Lifecourse Epidemiology Unit), Eugène McCloskey(Arthritis UK), Olivier Bruyère(University of Liège), Nicola Veronese(Neuroscience Institute), Mattias Lorentzon(Sahlgrenska University Hospital), Cyrus Cooper(University of Oxford), René Rizzoli(University Hospital of Geneva), Gemma Adib, Nasser M. Al‐Daghri(King Saud University), Claudia Campusano(Universidad de Los Andes, Chile), Manju Chandran(Singapore General Hospital), Bess Dawson‐Hughes(Tufts University), M K Javaid(University of Oxford), Famida Jiwa(Osteoporosis Canada), Helena Johansson(Australian Catholic University), J. K. Lee, Enwu Liu(Australian Catholic University), Daniel Messina(Argerich Hospital), O. Mkinsi(Centre Hospitalier Universitaire Ibn Rochd), Daniel Pinto(Marquette University), Daniel Prieto‐Alhambra(Universitat Autònoma de Barcelona), Kenneth G. Saag(University of Alabama at Birmingham), Weibo Xia(Chinese Academy of Medical Sciences & Peking Union Medical College), L. Zakraoui(Hôpital Mongi Slim), J. -Y. Reginster(University of Liège)
Osteoporosis International
November 13, 2019
10.1007/s00198-019-05176-3
Cited by 370Open Access
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Abstract

Guidance is provided in an international setting on the assessment and specific treatment of postmenopausal women at low, high and very high risk of fragility fractures. INTRODUCTION: The International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis published guidance for the diagnosis and management of osteoporosis in 2019. This manuscript seeks to apply this in an international setting, taking additional account of further categorisation of increased risk of fracture, which may inform choice of therapeutic approach. METHODS: Clinical perspective and updated literature search. RESULTS: The following areas are reviewed: categorisation of fracture risk and general pharmacological management of osteoporosis. CONCLUSIONS: A platform is provided on which specific guidelines can be developed for national use to characterise fracture risk and direct interventions.

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