Recent progress in drug delivery

Chong Li(Southwest University), Jiancheng Wang(Peking University), Yiguang Wang(Peking University), Huile Gao(Sichuan University), Gang Wei(Fudan University), Yongzhuo Huang(Shanghai Institute of Materia Medica), Haijun Yu(Chinese Academy of Sciences), Yong Gan(Shanghai Institute of Materia Medica), Yongjun Wang(State Key Laboratory of Natural and Biomimetic Drugs), Lin Mei(Sun Yat-sen University), Huabing Chen(Soochow University), Haiyan Hu(Sun Yat-sen University), Zhiping Zhang(Huazhong University of Science and Technology), Yiguang Jin
Acta Pharmaceutica Sinica B
August 19, 2019
Cited by 794Open Access
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Abstract

Drug delivery systems (DDS) are defined as methods by which drugs are delivered to desired tissues, organs, cells and subcellular organs for drug release and absorption through a variety of drug carriers. Its usual purpose to improve the pharmacological activities of therapeutic drugs and to overcome problems such as limited solubility, drug aggregation, low bioavailability, poor biodistribution, lack of selectivity, or to reduce the side effects of therapeutic drugs. During 2015-2018, significant progress in the research on drug delivery systems has been achieved along with advances in related fields, such as pharmaceutical sciences, material sciences and biomedical sciences. This review provides a concise overview of current progress in this research area through its focus on the delivery strategies, construction techniques and specific examples. It is a valuable reference for pharmaceutical scientists who want to learn more about the design of drug delivery systems.


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