Natural history and cell of origin of TCF3-ZNF384 and PTPN11 mutations in monozygotic twins with concordant BCP-ALL

Clara Bueno(Instituto de Salud Carlos III), Juan Ramón Tejedor(Instituto de Investigación Sanitaria del Principado de Asturias), Rachael Bashford-Rogers(Centre for Human Genetics), Laura González-Silva(Universidad de Cantabria), Rafael Valdés‐Mas, Antonio Agraz-Doblás(Universidad de Cantabria), Rafael Díaz de la Guardia(Josep Carreras Leukaemia Research Institute), Jordi Ribera(Josep Carreras Leukaemia Research Institute), Lurdes Zamora(Josep Carreras Leukaemia Research Institute), Chrystèle Bilhou‐Nabera(Inserm), Nasséra Abermil(Inserm), Hélène Guermouche(Inserm), Elodie Gouache(Sorbonne Université), Guy Leverger(Sorbonne Université), Mario F. Fraga(Universidad de Oviedo), Agustín F. Fernández(Instituto de Investigación Sanitaria del Principado de Asturias), Paola Ballerini(Sorbonne Université), Ignacio Varela(Universidad de Cantabria), Pablo Menéndez(Institució Catalana de Recerca i Estudis Avançats)
Blood
June 20, 2019
10.1182/blood.2019000893
Cited by 32Open Access
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Abstract

This work was supported by European Research Council grants CoG-2014-646903 and PoC-2018-811220 (P.M.) and StG-2014-637904 (I.V.), Generalitat de Catalunya grants SGR330 and PERIS 2017-2019 (P. M.), Spanish Ministry of Economy and Competitiveness grants SAF2016-80481-R and SAF2016-76758-R (P.M. and I.V.), Spanish Association Against Cancer grant AECC-CI-2015 (C.B.), Health Institute Carlos III grant PI17/01028 (C.B.), and a FERO Foundation grant (C.B.). P.M. also acknowledges financial support from the Obra Social La Caixa-Fundacio Josep Carreras and Fundacion Leo Messi. J.R.T. is supported by a Juan de la Cierva Formacion fellowship from the Spanish Ministry of Science and Innovation (FJCI-2015-26965) and Institute of Oncology of Asturias. R.V.-M. is supported by a Torres Quevedo fellowship from the Spanish Ministry of Science and Innovation (PTQ-16-08623). P.M. is an investigator of the Spanish Cell Therapy Cooperative Network.

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