The metastability of the proteome of spinal motor neurons underlies their selective vulnerability in ALS

Justin J. Yerbury(University of Wollongong), Michele Vendruscolo(University of Cambridge), Ian P. Blair(Macquarie University), Lezanne Ooi(University of Wollongong), Prajwal Ciryam(Columbia University), Christopher M. Dobson(University of Cambridge)
Neuroscience Letters
April 3, 2019
10.1016/j.neulet.2019.04.001
Cited by 27

Related Papers

An Analytical Solution to the Kinetics of Breakable Filament Assembly
|Science|2009|1.1k
Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis
|Nature|1997|1k
ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function
|Neuron|2015|917
TRPV3 is a temperature-sensitive vanilloid receptor-like protein
|Nature|2002|851
Half a century of amyloids: past, present and future
|Chemical Society Reviews|2020|585