The human body at cellular resolution: the NIH Human Biomolecular Atlas Program
Writing Group(Stanford Medicine), M Snyder(University of Washington), Shin Lin(University of Washington), Amanda L. Posgai(University of Florida), Mark A. Atkinson(Broad Institute), Aviv Regev(Broad Institute), Jennifer Rood(Broad Institute), Orit Rozenblatt–Rosen(Broad Institute), Leslie Gaffney(Broad Institute), Anna Hupalowska(Broad Institute), Rahul Satija(Harvard University), Nils Gehlenborg(Howard Hughes Medical Institute), Jay Shendure(Howard Hughes Medical Institute), Julia Laskin(Purdue University West Lafayette), Pehr Harbury(Pittsburgh Supercomputing Center), Nicholas A. Nystrom(University of Pittsburgh), Jonathan C. Silverstein(University of Pittsburgh), Ziv Bar‐Joseph(University of California San Diego), Kun Zhang(University of California San Diego), Katy Börner(Washington University in St. Louis), Yiing Lin(National Institutes of Health), Richard Conroy(National Institutes of Health), Dena Procaccini(National Institutes of Health), Ananda L. Roy(National Institutes of Health), Ajay Pillai(National Institutes of Health), Marishka Brown(National Institutes of Health), Zorina S. Galis(California Institute of Technology), Caltech-UW TMC(Howard Hughes Medical Institute), Long Cai(California Institute of Technology), Jay Shendure(Howard Hughes Medical Institute), Cole Trapnell(Howard Hughes Medical Institute), Shin Lin(University of Washington), Dana L. Jackson(Howard Hughes Medical Institute), Stanford-WashU TMC(Stanford Medicine), Michael P. Snyder(Washington University in St. Louis), Garry P. Nolan(Stanford Medicine), William J. Greenleaf(Stanford Medicine), Yiing Lin(Washington University in St. Louis), Sylvia K. Plevritis(Stanford Medicine), Sara Ahadi(Stanford Medicine), Stephanie Nevins(Stanford Medicine), Hayan Lee(Stanford Medicine), Christian Schuerch(Stanford Medicine), Sarah Black(Stanford Medicine), Vishal G. Venkataraaman(Stanford Medicine), Edward D. Esplin(University of California San Diego), Aaron Horning(University of California San Diego), Amir Bahmani(Washington University in St. Louis), UCSD TMC(University of North Carolina at Chapel Hill), Kun Zhang(University of California San Diego), Xin Sun(Harvard University), Sanjay Jain(Washington University in St. Louis), James S. Hagood(University of North Carolina at Chapel Hill), Gloria Pryhuber(University of Florida), Peter V. Kharchenko(Harvard University), Mark A. Atkinson(University of Florida), Bernd Bodenmiller(University of Zurich), Todd M. Brusko(University of Florida), Michael Clare‐Salzler(University of Florida), Harry S. Nick(University of Florida), Kevin J. Otto(University of Florida), Amanda L. Posgai(University of Zurich), Clive Wasserfall(Vanderbilt University), Marda Jorgensen(Vanderbilt University), Maigan Brusko(Vanderbilt University), Sergio Maffioletti(Vanderbilt University), Richard M. Caprioli(Vanderbilt University), Jeffrey M. Spraggins(Vanderbilt University), Danielle Gutierrez(Vanderbilt University), Nathan Heath Patterson(Vanderbilt University), Elizabeth K. Neumann(Vanderbilt University), Raymond C. Harris(Vanderbilt University), Mark deCaestecker(California Institute of Technology), Agnes B. Fogo(Dana-Farber Cancer Institute), Raf Van de Plas(Dana-Farber Cancer Institute), Ken S. Lau(Vanderbilt University), Long Cai(California Institute of Technology), Guo‐Cheng Yuan(Dana-Farber Cancer Institute), Qian Zhu(Dana-Farber Cancer Institute), Ruben Dries(Dana-Farber Cancer Institute), Harvard TTD, Peng Yin(Harvard University), Sinem K. Saka(Marquette University), Jocelyn Y. Kishi(Harvard University), Yu Wang(Harvard University), Isabel Goldaracena(Harvard University), Purdue TTD(Pacific Northwest National Laboratory), Julia Laskin(Purdue University West Lafayette), DongHye Ye(Marquette University), Kristin Burnum-Johnson(Pacific Northwest National Laboratory), Paul Piehowski(Pacific Northwest National Laboratory), Charles Ansong(Pacific Northwest National Laboratory), Ying Zhu(Pacific Northwest National Laboratory), Stanford TTD(Wellcome Sanger Institute), Pehr Harbury(University of California, Santa Cruz), Tushar Desai(Carnegie Mellon University), Jay Mulye(Carnegie Mellon University), Peter Chou(Wellcome Sanger Institute), Monica Nagendran(Carnegie Mellon University), Ziv Bar‐Joseph(Carnegie Mellon University), Sarah A. Teichmann(Wellcome Sanger Institute), Benedict Paten(University of California, Santa Cruz), Robert F. Murphy(Carnegie Mellon University), Jian Ma(Harvard University), Vladimir Yu Kiselev(Harvard University), Carl Kingsford(Harvard University), Allyson Ricarte(Harvard University), Maria Keays(Wellcome Sanger Institute), Sushma A. Akoju(Indiana University Bloomington), Matthew Ruffalo(Opto-Knowledge Systems (United States)), Nils Gehlenborg(Harvard University), Peter V. Kharchenko(Harvard University), Margaret E. Vella(Harvard University), Chuck McCallum(Harvard University), Katy Börner(Indiana University Bloomington), Leonard E. Cross(Indiana University Bloomington), Samuel H. Friedman(Harvard University), Randy Heiland(Pittsburgh Supercomputing Center), Bruce Herr(University of Pittsburgh), Paul Macklin(Pittsburgh Supercomputing Center), Ellen M. Quardokus(Pittsburgh Supercomputing Center), Lisel Record(University of Pittsburgh), James P. Sluka(Pittsburgh Supercomputing Center), Griffin M. Weber(Harvard University), Nicholas A. Nystrom(Pittsburgh Supercomputing Center), Jonathan C. Silverstein(University of Pittsburgh), Philip D. Blood(Pittsburgh Supercomputing Center), Alexander J. Ropelewski(Pittsburgh Supercomputing Center), William Shirey(University of Pittsburgh), Robin Scibek(Howard Hughes Medical Institute), Paula Mabee(University of South Dakota), W. Christopher Lenhardt(New York Genome Center), Kimberly Robasky(University of North Carolina at Chapel Hill), Stavros Michailidis(University of Cambridge), Rahul Satija(Broad Institute), John C. Marioni(Broad Institute), Aviv Regev(Broad Institute), Andrew Butler(Broad Institute), Tim Stuart(Broad Institute), Eyal Fisher(National Institutes of Health), Shila Ghazanfar(National Institutes of Health), Jennifer Rood(Broad Institute), Leslie Gaffney(Broad Institute), Gökçen Eraslan(Broad Institute), Tommaso Biancalani(Broad Institute), Eeshit Dhaval Vaishnav(Broad Institute), NIH HuBMAP Working Group(National Institutes of Health), Richard Conroy(National Institutes of Health), Dena Procaccini(National Institutes of Health), Ananda L. Roy(National Institutes of Health), Ajay Pillai(National Institutes of Health), Marishka Brown(National Institutes of Health), Zorina S. Galis(National Institutes of Health), Pothur R. Srinivas(National Institutes of Health), Aaron C. Pawlyk(National Institutes of Health), Salvatore Sechi(National Institutes of Health), Elizabeth L. Wilder(National Institutes of Health), James M. Anderson(National Institutes of Health)
Cited by 663Open Access
Abstract
Transformative technologies are enabling the construction of three-dimensional maps of tissues with unprecedented spatial and molecular resolution. Over the next seven years, the NIH Common Fund Human Biomolecular Atlas Program (HuBMAP) intends to develop a widely accessible framework for comprehensively mapping the human body at single-cell resolution by supporting technology development, data acquisition, and detailed spatial mapping. HuBMAP will integrate its efforts with other funding agencies, programs, consortia, and the biomedical research community at large towards the shared vision of a comprehensive, accessible three-dimensional molecular and cellular atlas of the human body, in health and under various disease conditions.
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