A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function
Jie Gao(Southern Medical University), Yubin Li(Southern Medical University), Yu Wan(Southern Medical University), Tongtong Hu(Southern Medical University), Liting Liu(Dali University), Shaojie Yang(Southern Medical University), Zelong Gong(Southern Medical University), Qing Zeng(Southern Medical University), Wei Yi(Southern Medical University), Weijun Yang(Southern Medical University), Zhijie Zeng(Southern Medical University), Xiaolong He(Southern Medical University), Sheng‐He Huang(Children's Hospital of Los Angeles), Hong Cao(Southern Medical University)
Cited by 276Open Access
Abstract
K1 pathogenesis. Moreover, we further extended the role of HM0539 and found it has potential to prevent dextran sulfate sodium (DSS)-induced colitis as well as LPS/D-galactosamine-induced bacterial translocation and liver injury. In conclusion, we identified a novel LGG postbiotic HM0539 which exerts a protective effect on intestinal barrier function. Our findings indicated that HM0539 has potential to become a useful agent for prevention and treatment of intestinal barrier dysfunction- related diseases.
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