Binodal, wireless epidermal electronic systems with in-sensor analytics for neonatal intensive care

Ha Uk Chung(Northwestern University), Bong Hoon Kim(Northwestern University), Jong Yoon Lee(University of Illinois Urbana-Champaign), Jungyup Lee(University of Illinois Urbana-Champaign), Zhaoqian Xie(Northwestern University), Erin Ibler(Northwestern University), KunHyuck Lee(Northwestern University), Anthony Banks(Northwestern University), Ji Yoon Jeong(University of Illinois Urbana-Champaign), Jong-Won Kim(Northwestern University), Christopher Ogle(Northwestern University), Dominic Grande(University of Illinois Urbana-Champaign), Yongjoon Yu(University of Illinois Urbana-Champaign), Hokyung Jang(University of Illinois Urbana-Champaign), Pourya Assem(University of Illinois Urbana-Champaign), Dennis Ryu(Northwestern University), Jean Won Kwak(Northwestern University), Myeong Namkoong(Northwestern University), Jun Bin Park(University of Illinois Urbana-Champaign), Yechan Lee(University of Illinois Urbana-Champaign), Do Hoon Kim(University of Illinois Urbana-Champaign), Arin Ryu(University of Illinois Urbana-Champaign), Jaeseok Jeong(University of Illinois Urbana-Champaign), Kevin You(University of Illinois Urbana-Champaign), Bowen Ji(Northwestern University), Zhuangjian Liu(Institute of High Performance Computing), Qingze Huo(Northwestern University), Xue Feng(Tsinghua University), Yujun Deng(Northwestern University), Yeshou Xu(Northwestern University), Kyung‐In Jang(Daegu Gyeongbuk Institute of Science and Technology), Jeonghyun Kim(Northwestern University), Yihui Zhang(Tsinghua University), Roozbeh Ghaffari(Northwestern University), Casey M. Rand(Lurie Children's Hospital), Molly Schau(Lurie Children's Hospital), Aaron Hamvas(Lurie Children's Hospital), Debra E. Weese‐Mayer(Lurie Children's Hospital), Yonggang Huang(Northwestern University), Seung Min Lee(Kookmin University), Chi Hwan Lee(Purdue University West Lafayette), Naresh R. Shanbhag(University of Illinois Urbana-Champaign), Amy S. Paller(Northwestern University), Shuai Xu(Northwestern University), John A. Rogers(Northwestern University)
Science
March 1, 2019
Cited by 776Open Access
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Abstract

Existing vital sign monitoring systems in the neonatal intensive care unit (NICU) require multiple wires connected to rigid sensors with strongly adherent interfaces to the skin. We introduce a pair of ultrathin, soft, skin-like electronic devices whose coordinated, wireless operation reproduces the functionality of these traditional technologies but bypasses their intrinsic limitations. The enabling advances in engineering science include designs that support wireless, battery-free operation; real-time, in-sensor data analytics; time-synchronized, continuous data streaming; soft mechanics and gentle adhesive interfaces to the skin; and compatibility with visual inspection and with medical imaging techniques used in the NICU. Preliminary studies on neonates admitted to operating NICUs demonstrate performance comparable to the most advanced clinical-standard monitoring systems.


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