The UCSC Genome Browser Database: update 2009

Robert M. Kuhn(University of California, Santa Cruz), Donna Karolchik(Pennsylvania State University), Ann S. Zweig(Pennsylvania State University), T. Wang(Howard Hughes Medical Institute), Kayla Smith(Howard Hughes Medical Institute), Kate R. Rosenbloom(Pennsylvania State University), Brooke Rhead(Howard Hughes Medical Institute), Brian J. Raney(Howard Hughes Medical Institute), A. Pohl(University of California, Santa Cruz), Michael Pheasant(Howard Hughes Medical Institute), Laurence Meyer(Pennsylvania State University), F. Hsu(University of California, Santa Cruz), Angie S. Hinrichs(Howard Hughes Medical Institute), Rachel Harte(Howard Hughes Medical Institute), Belinda Giardine(Howard Hughes Medical Institute), Pauline A. Fujita(University of California, Santa Cruz), Mark Diekhans(Pennsylvania State University), Timothy R. Dreszer(University of California, Santa Cruz), Hiram Clawson(Pennsylvania State University), G. P. Barber(Howard Hughes Medical Institute), David Haussler(Howard Hughes Medical Institute), W. James Kent(University of California, Santa Cruz)
Nucleic Acids Research
November 8, 2008
Cited by 385Open Access
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Abstract

The UCSC Genome Browser Database (GBD, http://genome.ucsc.edu) is a publicly available collection of genome assembly sequence data and integrated annotations for a large number of organisms, including extensive comparative-genomic resources. In the past year, 13 new genome assemblies have been added, including two important primate species, orangutan and marmoset, bringing the total to 46 assemblies for 24 different vertebrates and 39 assemblies for 22 different invertebrate animals. The GBD datasets may be viewed graphically with the UCSC Genome Browser, which uses a coordinate-based display system allowing users to juxtapose a wide variety of data. These data include all mRNAs from GenBank mapped to all organisms, RefSeq alignments, gene predictions, regulatory elements, gene expression data, repeats, SNPs and other variation data, as well as pairwise and multiple-genome alignments. A variety of other bioinformatics tools are also provided, including BLAT, the Table Browser, the Gene Sorter, the Proteome Browser, VisiGene and Genome Graphs.


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