Mafb and c-Maf Have Prenatal Compensatory and Postnatal Antagonistic Roles in Cortical Interneuron Fate and Function

Emily Ling-Lin Pai(University of California, San Francisco), Daniel Vogt(University of California, San Francisco), Alexandra Clemente-Perez(Gladstone Institutes), Gabriel L. McKinsey(University of California, San Francisco), Frances S. Cho(Gladstone Institutes), Jia Sheng Hu(University of California, San Francisco), Matt Wimer(Gladstone Institutes), Anirban Paul(Cold Spring Harbor Laboratory), Siavash Fazel Darbandi(University of California, San Francisco), Ramón Pla(University of California, San Francisco), Tomasz J. Nowakowski(University of California, San Francisco), Lisa V. Goodrich(Harvard University), Jeanne T. Paz(Gladstone Institutes), John L.R. Rubenstein(University of California, San Francisco)
Cell Reports
January 1, 2019
10.1016/j.celrep.2019.01.031
Cited by 75Open Access
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Abstract

cortical and hippocampal interneurons. By contrast, Mafb and c-Maf have distinct roles in postnatal cortical interneuron (CIN) morphological maturation, synaptogenesis, and cortical circuit integration. Thus, Mafb and c-Maf have redundant and opposing functions at different steps in CIN development.

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