SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis

Guihua Wang(Hengyang Academy of Agricultural Sciences), Hui‐Kuan Lin(Duke University), Min Gyu Lee(The University of Texas MD Anderson Cancer Center), Tsai‐Yu Chen(The University of Texas MD Anderson Cancer Center), Guoxiang Jin(Guangdong Academy of Medical Sciences), Zhenlin Hou(Sun Yat-sen University), Jingqin Lan(Tongji Hospital), Jie Long(Shanghai University of Traditional Chinese Medicine), Chuan Xu(University of Electronic Science and Technology of China), Hongyu Li(Xijing Hospital), Fei Han(Shenyang Pharmaceutical University), Zhen Cai(Atrium Health Wake Forest Baptist), Weina Zhang(Gansu Agricultural University), Yuan Gao(Brigham and Women's Hospital), Li Sun(Atrium Health Wake Forest Baptist), Shun-Chin Yang(Atrium Health Wake Forest Baptist), Junbo Hu(Tongji Hospital), Che-Chia Hsu(Taipei Medical University), Yu-Hui Wang(Peking University)
Nature Cell Biology
January 28, 2019
10.1038/s41556-018-0266-1
Cited by 204

Related Papers

M2 Macrophage-Derived Exosomes Promote Cell Migration and Invasion in Colon Cancer
|Cancer Research|2018|672
Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS
|Cell|2019|601
The Mechanisms of PML-Nuclear Body Formation
|Molecular Cell|2006|517
Tumor-derived lactate promotes resistance to bevacizumab treatment by facilitating autophagy enhancer protein RUBCNL expression through histone H3 lysine 18 lactylation (H3K18la) in colorectal cancer
|Autophagy|2023|387
Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis
|Molecular Cell|2020|266