Cervical Cancer, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology

Wui-Jin Koh(Cancer Research Center), Nadeem R. Abu‐Rustum(Memorial Sloan Kettering Cancer Center), Sarah M. Bean(Duke Cancer Institute), Kristin Bradley(University of Wisconsin Carbone Cancer Center), Susana M. Campos(Dana-Farber Brigham Cancer Center), Kathleen R. Cho(University of Michigan–Ann Arbor), Hye Sook Chon(Moffitt Cancer Center), Christina Chu(Fox Chase Cancer Center), Rachel Clark(Massachusetts General Hospital), David E. Cohn(Vanderbilt-Ingram Cancer Center), Marta A. Crispens, Shari Damast(Yale Cancer Center), Oliver Dorigo(Stanford Cancer Institute), Patricia J. Eifel(The University of Texas MD Anderson Cancer Center), Christine M. Fisher(University of Colorado Cancer Center), Peter J. Frederick, David K. Gaffney(University of Utah), Ernest Han(City Of Hope National Medical Center), Warner K. Huh(University of Alabama at Birmingham), John R. Lurain, Andrea Mariani(WinnMed), David G. Mutch(Jewish Hospital), Christa Nagel(University Hospitals Seidman Cancer Center), Larissa Nekhlyudov(Dana-Farber Brigham Cancer Center), Amanda N. Fader(Fred and Pamela Buffett Cancer Center), Steven W. Remmenga, R. Kevin Reynolds(University of Michigan–Ann Arbor), Todd Tillmanns(University of Tennessee Health Science Center), Stefanie Ueda(UCSF Helen Diller Family Comprehensive Cancer Center), Emily Wyse, Catheryn M. Yashar(UC San Diego Health System), Nicole R. McMillian(National Comprehensive Cancer Network), Jillian L. Scavone(National Comprehensive Cancer Network)
Journal of the National Comprehensive Cancer Network
January 1, 2019
Cited by 1,066

Abstract

Cervical cancer is a malignant epithelial tumor that forms in the uterine cervix. Most cases of cervical cancer are preventable through human papilloma virus (HPV) vaccination, routine screening, and treatment of precancerous lesions. However, due to inadequate screening protocols in many regions of the world, cervical cancer remains the fourth-most common cancer in women globally. The complete NCCN Guidelines for Cervical Cancer provide recommendations for the diagnosis, evaluation, and treatment of cervical cancer. This manuscript discusses guiding principles for the workup, staging, and treatment of early stage and locally advanced cervical cancer, as well as evidence for these recommendations. For recommendations regarding treatment of recurrent or metastatic disease, please see the full guidelines on NCCN.org.


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