Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12a.

Daan C. Swarts(University of Zurich), Martin Jínek(University of Zurich)

PubMed

February 7, 2019

10.1016/j.molcel.2018.11.021

Cited by 220

Related Papers

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

|Science|2012|17.2k

RNA-programmed genome editing in human cells

|eLife|2013|2.1k

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9

|Nature|2014|1.9k

Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease

|Nature|2014|1.4k

Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

|Science|2014|1.3k