The Nucleotide Kinase Nadk Is Required for ROS Detoxification and Constitutes a Metabolic Vulnerability of NOTCH1-Driven T-ALL
Étienne De Braekeleer(Wellcome Sanger Institute), George S. Vassiliou(Wellcome/MRC Cambridge Stem Cell Institute), Stefano Indraccolo(University of Padua), Alan J. Warren(Wellcome/MRC Cambridge Stem Cell Institute), David Fernández Antorán(Wellcome Sanger Institute), Irmela Jeremias(Helmholtz Zentrum München), Joanne I. Hsu(Brigham and Women's Hospital), Margaret A. Goodell(Baylor College of Medicine), Konstantinos Tzelepis(Wellcome/MRC Cambridge Stem Cell Institute), Phil Jones(Wellcome Sanger Institute), Celine Hervieu(Wellcome Sanger Institute)
Cited by 2
Related Papers
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
|The Lancet|2005|3.4k
Somatic<i>SF3B1</i>Mutation in Myelodysplasia with Ring Sideroblasts
|New England Journal of Medicine|2011|1.2k
A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia
|Cell Reports|2016|834
PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy
|Cell stem cell|2018|423
METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation
|Molecular Cell|2021|359