Identification of a cellularly active SIRT6 allosteric activator

Zhimin Huang(Shenzhen Luohu People's Hospital), Jian Zhang(Shanxi Medical University), Zhiyong Mao(Shanghai First Maternity and Infant Hospital), Ying‐Yi Chen(Chang Gung University), Xiuyan Yang(Shanghai Jiao Tong University), Xiaoxiang Sun(Tongji University), Ying Xu(Soochow University), Hou‐Wen Lin(Shanghai Jiao Tong University), Y. Eugene Chin(Rhode Island Hospital), Shaoyong Lu(Shanghai Jiao Tong University), Kun Song(Heidelberg University), Hao Hu(Beijing Tongren Hospital), Junxing Zhao(Shanghai Jiao Tong University), Bin He(Guiyang Medical University), Minjia Tan(Chinese Academy of Sciences), Qiufen Zhang(Yellow River Institute of Hydraulic Research), Jianrong Xu(Shanghai Jiao Tong University), Chengxiang Wang(Shanghai Jiao Tong University), Jie Zhong(Shanghai Jiao Tong University), Lu Zhang(Guilin University of Technology), Guoqiang Chen(Shanghai Jiao Tong University), Jialin Shang(State Key Laboratory of Oncogene and Related Genes), Wei Deng(Hunan Agricultural University), Hualiang Jiang(Shanghai Institute of Materia Medica), Mingzhe Xiao(Chinese Academy of Sciences), Jinrong Min(Structural Genomics Consortium)
Nature Chemical Biology
October 23, 2018
10.1038/s41589-018-0150-0
Cited by 272

Related Papers

Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase
|Science|2011|1.4k
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
|Nature|2015|827
SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine
|Nature|2013|706
Structure and function of WD40 domain proteins
|Protein & Cell|2011|653
Integrative Proteomic Characterization of Human Lung Adenocarcinoma
|Cell|2020|634