Discovery and Structure–Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-<scp>d</scp>-ribose 2′-Oxidase

Sangmi Oh(Institut Pasteur Korea), Clifton E. Barry(National Institutes of Health), Joshua B. Wallach(Cornell University), Nicholas Murgolo(Merck & Co., Inc., Rahway, NJ, USA (United States)), Michael Goodwin(National Institutes of Health), Dirk Schnappinger(Cornell University), Helena I. Boshoff(National Institutes of Health), Kriti Arora(National Institutes of Health), Brian Gac(National Institutes of Health), Yumi Park(Inje University), Curtis A. Engelhart(Cornell University), Michelle Manikkam(National Institutes of Health), Michelle Sutphin(National Institutes of Health), David B. Olsen, Hongwu Wang(Meitan General Hospital), Laura E. Via(National Institutes of Health)

Journal of Medicinal Chemistry

October 10, 2018

Cited by 37

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Discovery and Structure–Activity-Relationship Study of <i>N</i>-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-<scp>d</scp>-ribose 2′-Oxidase