HiGlass: web-based visual exploration and analysis of genome interaction maps
Peter Kerpedjiev(Harvard University), Nezar Abdennur, Fritz Lekschas(Harvard University), Chuck McCallum(Harvard University), Kasper Dinkla(Harvard University), Hendrik Strobelt(Harvard University), Jacob M. Luber(Harvard University), Scott Ouellette(Harvard University), Alaleh Azhir(Harvard University), Nikhil Kumar(Harvard University), Jeewon Hwang(Harvard University), Soohyun Lee(Harvard University), B. Alver(Harvard University), Hanspeter Pfister(Harvard University), Leonid A. Mirny(IIT@MIT), Peter J. Park(Harvard University), Nils Gehlenborg(Harvard University)
Cited by 2,268Open Access
Abstract
We present HiGlass, an open source visualization tool built on web technologies that provides a rich interface for rapid, multiplex, and multiscale navigation of 2D genomic maps alongside 1D genomic tracks, allowing users to combine various data types, synchronize multiple visualization modalities, and share fully customizable views with others. We demonstrate its utility in exploring different experimental conditions, comparing the results of analyses, and creating interactive snapshots to share with collaborators and the broader public. HiGlass is accessible online at http://higlass.io and is also available as a containerized application that can be run on any platform.