Chimeric Antigen Receptor Therapy
Carl H. June(Memorial Sloan Kettering Cancer Center), Michel Sadelain(Memorial Sloan Kettering Cancer Center)
Cited by 2,245Open Access
Abstract
Interview with Dr. Carl June on chimeric antigen receptor therapy. (09:04)Download This review addresses T-cell engineering and synthetic immunity, with a focus on producing durable remissions in patients with treatment-refractory tumors. Toxic effects of chimeric antigen receptor therapies include cytokine release syndrome and neurologic dysfunction.
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