Mediator and RNA polymerase II clusters associate in transcription-dependent condensates

Won‐Ki Cho(IIT@MIT), Ibrahim I. Cissé(Massachusetts Institute of Technology), Jan-Hendrik Spille(University of Illinois Chicago), Choongman Lee(Max Planck Institute of Immunobiology and Epigenetics), Charles H. Li(IIT@MIT), Micca Hecht(IIT@MIT), Valentin Grube(LMU Klinikum)
Science
June 21, 2018
10.1126/science.aar4199
Cited by 1,512

Related Papers

Pol II phosphorylation regulates a switch between transcriptional and splicing condensates
|Nature|2019|725
Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes
|Molecular Cell|2019|302
RNA Polymerase II cluster dynamics predict mRNA output in living cells
|eLife|2016|301
Direct observation of a condensate effect on super-enhancer controlled gene bursting
|Cell|2024|166
A first order phase transition mechanism underlies protein aggregation in mammalian cells
|eLife|2019|108