Comprehensive Cancer-Predisposition Gene Testing in an Adult Multiple Primary Tumor Series Shows a Broad Range of Deleterious Variants and Atypical Tumor Phenotypes

James Whitworth(University of Cambridge), Keren Carss(AstraZeneca (United Kingdom)), Jonathan Hoffman(Birmingham Women's Hospital), Hassan Shakeel(University of Cambridge), Helen Hanson(University of Exeter), Hana Alachkar, Sonia Ali(University of Swabi), Richard Antrobus(University of Oxford), Karyn Mégy(AstraZeneca (United Kingdom)), Julian Adlard(Chapel Allerton Hospital), Ava Kwong(University of Hong Kong), Lynn Greenhalgh, David Allsup(University of Leeds), Jose‐Ezequiel Martín(University of Cambridge), Philip Smith(Roche (Sweden)), Louise Allen(St Thomas' Hospital), Emma R. Woodward(Royal Manchester Children's Hospital), Louise Izatt(Guy's and St Thomas' NHS Foundation Trust), Rutendo Mapeta(NHS Blood and Transplant), Timothy J. Aitman(Institute of Genetics and Cancer), Claire Searle(Nottingham University Hospitals NHS Trust), Ruth Casey(Wellcome/MRC Institute of Metabolic Science), Soo‐Mi Park(Cambridge University Hospitals NHS Foundation Trust), Lucy Side(Unknown), Kathleen Stirrups(Queen Mary University of London), Julie Anderson, Rakefet Chen‐Shtoyerman(Kaplan Medical Center), Jonathan Stephens(NHS Blood and Transplant), Julian Barwell(London North West Healthcare NHS Trust), Fiona Lalloo(St Mary's Hospital), Ajith Kumar(Great Ormond Street Hospital), Graeme M. Clark(Cancer Research UK), Sofie Ashford(University of Cambridge), Chris Penkett(NHS Blood and Transplant), Katie Snape(Institute of Cancer Research), Gautum Ambegaonkar, D. Gareth Evans(Manchester Academic Health Science Centre), Faye Rodger(University of Cambridge), Munaza Ahmed(Great Ormond Street Hospital), Hannah D. West(University of Cambridge), Anne‐Bine Skytte(Aarhus University Hospital), Andrea Luchetti(University of Cambridge), Trevor Cole(Birmingham Women's Hospital), Carole Brewer(Royal Devon and Exeter Hospital), Alex Henderson(Centre for Life), Joan Paterson, Kai Ren Ong(Birmingham Women's Hospital), Florentia Fostira(National Centre of Scientific Research "Demokritos"), Ruth Armstrong(University of Cambridge)
The American Journal of Human Genetics
June 14, 2018
Cited by 73


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