Acute kidney injury in major abdominal surgery: incidence, risk factors, pathogenesis and outcomes
Joana Gameiro(Centro Hospitalar Lisboa Norte), José Agapito Fonseca(Centro Hospitalar Lisboa Norte), Marta Neves(Centro Hospitalar Lisboa Norte), Sofía Jorge(Centro Hospitalar Lisboa Norte), José António Lopes(Centro Hospitalar Lisboa Norte)
Cited by 212Open Access
Abstract
Acute kidney injury (AKI) is a common complication in patients undergoing major abdominal surgery. Various recent studies using modern standardized classifications for AKI reported a variable incidence of AKI after major abdominal surgery ranging from 3 to 35%. Several patient-related, procedure-related factors and postoperative complications were identified as risk factors for AKI in this setting. AKI following major abdominal surgery has been shown to be associated with poor short- and long-term outcomes. Herein, we provide a contemporary and critical review of AKI after major abdominal surgery focusing on its incidence, risk factors, pathogeny and outcomes.