Identification of rare sequence variation underlying heritable pulmonary arterial hypertension

Stefan Gräf(University of Cambridge), Nicholas W. Morrell(University of Cambridge)

Nature Communications

April 11, 2018

10.1038/s41467-018-03672-4

Cited by 380

Related Papers

Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension

|Nature Medicine|2015|503

Altered Bone Morphogenetic Protein and Transforming Growth Factor-β Signaling in Rat Models of Pulmonary Hypertension

|Circulation|2009|258

TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling

|Nature Communications|2017|229

The lysosomal inhibitor, chloroquine, increases cell surface BMPR-II levels and restores BMP9 signalling in endothelial cells harbouring BMPR-II mutations

|Human Molecular Genetics|2013|100

Bone morphogenetic protein 9 (BMP9) and BMP10 enhance tumor necrosis factor-α-induced monocyte recruitment to the vascular endothelium mainly via activin receptor-like kinase 2

|Journal of Biological Chemistry|2017|56