Mathematical and Experimental Validation of Flux Dialysis Method: An Improved Approach to Measure Unbound Fraction for Compounds with High Protein Binding and Other Challenging Properties
J. Cory Kalvass(AbbVie (United States)), Volker Fischer(AbbVie (United States)), Marjoleen Nijsen(AbbVie (United States)), Colin Phipps(AbbVie (United States)), Patricia Stuart(AbbVie (United States)), Lance Heinle(AbbVie (United States)), Xiaomei Zhang(The University of Texas MD Anderson Cancer Center), Gary J. Jenkins(AbbVie (United States))
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