Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
Rainer Malik(LMU Klinikum), Ganesh Chauhan(Indian Institute of Science Bangalore), Matthew Traylor(Université de Bordeaux), Muralidharan Sargurupremraj(University of Cambridge), Yukinori Okada(RIKEN Center for Integrative Medical Sciences), Aniket Mishra(University of Cambridge), Loes C.A. Rutten‐Jacobs(Université de Bordeaux), Anne-Katrin Giese(Harvard University), Sander W. van der Laan(Utrecht University), Sólveig Grétarsdóttir(deCODE Genetics (Iceland)), Christopher D. Anderson(Broad Institute), Michael Chong(Population Health Research Institute), Hieab H.H. Adams(Erasmus MC), Tetsuro Ago(Kyushu University), Peter Almgren(Lund University), Philippe Amouyel(Inserm), Hakan Ay(Harvard University), Traci M. Bartz(University of Washington), Oscar R. Benavente(University of British Columbia), Steve Bevan(University of Lincoln), Giorgio B. Boncoraglio(Fondazione IRCCS Istituto Neurologico Carlo Besta), Robert D. Brown(Mayo Clinic), Adam S. Butterworth(University of Cambridge), Caty Carrera(Universitat Autònoma de Barcelona), Cara L. Carty(Children's National), Daniel I. Chasman(Brigham and Women's Hospital), Wei‐Min Chen(University of Virginia), John W. Cole(University of Maryland, Baltimore), Adolfo Correa(University of Mississippi Medical Center), Ioana Cotlarciuc(Royal Holloway University of London), Carlos Cruchaga(Washington University in St. Louis), John Danesh(University of Cambridge), Paul I. W. de Bakker(University Medical Center Utrecht), Anita L. DeStefano(Boston University), Marcel den Hoed(Uppsala University), Qing Duan(University of North Carolina at Chapel Hill), Stefan T. Engelter(University of Basel), Guido J. Falcone(Broad Institute), Rebecca F. Gottesman(Johns Hopkins University), Raji P. Grewal, Vilmundur Guðnason(University of Iceland), Stefan Gustafsson(Uppsala University), Jeffrey Haessler(Fred Hutch Cancer Center), Tamara B. Harris(National Institutes of Health), Ahamad Hassan(Leeds General Infirmary), Aki S. Havulinna(Finnish Institute for Health and Welfare), Susan R. Heckbert(University of Washington), Elizabeth G. Holliday(Hunter Medical Research Institute), George Howard(University of Alabama at Birmingham), Fang‐Chi Hsu(Wake Forest University), Hyacinth I. Hyacinth(Emory University), M. Arfan Ikram(Erasmus MC), Erik Ingelsson(Uppsala University), Marguerite R. Irvin(University of Alabama at Birmingham), Xueqiu Jian(Brown Foundation), Jordi Jiménez‐Conde(Universitat Autònoma de Barcelona), Julie A. Johnson(University of Florida), J. Wouter Jukema(Leiden University Medical Center), Masahiro Kanai(Harvard University), Keith L. Keene(East Carolina University), Brett Kissela(University of Cincinnati Medical Center), Dawn Kleindorfer(University of Cincinnati Medical Center), Charles Kooperberg(Fred Hutch Cancer Center), Michiaki Kubo(RIKEN Center for Integrative Medical Sciences), Leslie A. Lange(University of Colorado Anschutz Medical Campus), Carl D. Langefeld, Claudia Langenberg(University of Cambridge), Lenore J. Launer(National Institutes of Health), Jin‐Moo Lee(Washington University in St. Louis), Robin Lemmens(VIB-KU Leuven Center for Brain & Disease Research), Didier Leys(Inserm), Cathryn M. Lewis(King's College London), Wei‐Yu Lin(University of Cambridge), Arne G. Lindgren(Lund University), Erik Lorentzen(University of Gothenburg), Patrik K. E. Magnusson(Karolinska Institutet), Jane Maguire(University of Technology Sydney), Ani Manichaikul(University of Virginia), Patrick F. McArdle(University of Maryland, Baltimore), James F. Meschia(WinnMed), Braxton D. Mitchell(University of Maryland, Baltimore), Thomas H. Mosley(University of Mississippi Medical Center), Michael A. Nalls(National Institutes of Health), Toshiharu Ninomiya(Kyushu University), Martin O’Donnell(Population Health Research Institute), Bruce M. Psaty(Kaiser Permanente Washington Health Research Institute), Sara L. Pulit(University Medical Center Utrecht), Kristiina Rannikmäe(University of Edinburgh), Alex P. Reiner(University of Washington), Kathryn M. Rexrode(Brigham and Women's Hospital), Kenneth Rice(University of Washington), Stephen S. Rich(University of Virginia), Paul M. Ridker(Brigham and Women's Hospital), Natalia S. Rost(Harvard University), Peter M. Rothwell(University of Oxford), Jerome I. Rotter(The Lundquist Institute), Tatjana Rundek(University of Miami), Ralph L. Sacco(University of Miami), Saori Sakaue(The University of Tokyo), Michèle M. Sale(University of Virginia), Veikko Salomaa(Finnish Institute for Health and Welfare), Bishwa R. Sapkota(Medical University of Graz), Reinhold Schmidt(Medical University of Graz), Carsten Oliver Schmidt(Universitätsmedizin Greifswald), Ulf Schminke(Royal Holloway University of London), Pankaj Sharma(Jagiellonian University), Agnieszka Slowik(Jagiellonian University), Cathie Sudlow(Justus-Liebig-Universität Gießen), Christian Tanislav(Justus-Liebig-Universität Gießen), Turgut Tatlisumak(The Lundquist Institute), Kent D. Taylor(The University of Melbourne), Vincent Thijs(deCODE Genetics (Iceland)), Gudmar Thorleifsson(deCODE Genetics (Iceland)), U. Thorsteinsdottir(deCODE Genetics (Iceland)), Steffen Tiedt(Leiden University Medical Center), Stella Trompet(Leiden University Medical Center), Christophe Tzourio(Inserm), Cornelia M. van Duijn(Erasmus MC), Matthew Walters(University of Cambridge), Nicholas J. Wareham(Albert Einstein College of Medicine), Sylvia Wassertheil-Smoller(Albert Einstein College of Medicine), James G. Wilson(University of Washington), Kerri L. Wiggins(Boston University), Qiong Yang(Boston University), Salim Yusuf(University of Washington), STARNET(McGill University), Joshua C. Bis(University of Washington), Tomi Pastinen(McGill University), Arno Ruusalepp(Tartu University Hospital), Eric E. Schadt(Icahn School of Medicine at Mount Sinai), Simon Koplev(Inserm), Johan Björkegren(Karolinska University Hospital), Veronica Codoni(Inserm), Mete Civelek(Inserm), Nicholas Smith(Broad Institute), David‐Alexandre Trégouët(Broad Institute), Ingrid E. Christophersen(Broad Institute), Carolina Roselli(Broad Institute), Steven A. Lubitz(Broad Institute), Patrick T. Ellinor(Broad Institute), E. Shyong Tai(National University of Singapore), Jaspal S. Kooner(Tulane University), Norihiro Kato(University Medical Center Groningen), Jiang He(Tulane University), Pim van der Harst(University Medical Center Groningen), Paul Elliott(National Center for Global Health and Medicine), John C. Chambers(Ealing Hospital), Fumihiko Takeuchi(LMU Klinikum), Andrew D. Johnson(Framingham Heart Study), NINDS Stroke Genetics Network (SiGN)(Université de Bordeaux), UK Young Lacunar DNA Study(Institut des Maladies Neurodégénératives), Rainer Malik(LMU Klinikum), Ganesh Chauhan(Institut des Maladies Neurodégénératives), Matthew Traylor(Université de Bordeaux), Muralidharan Sargurupremraj(Harvard University), Yukinori Okada(Utrecht University), Aniket Mishra(deCODE Genetics (Iceland)), Loes C.A. Rutten‐Jacobs(Broad Institute), Anne-Katrin Giese(Harvard University), Sander W. van der Laan(Utrecht University), Sólveig Grétarsdóttir(deCODE Genetics (Iceland)), Christopher D. Anderson(Broad Institute), Michael Chong(Population Health Research Institute), Hieab H.H. Adams(Harvard University), Tetsuro Ago(Kyushu University), Peter Almgren(University of British Columbia), Philippe Amouyel(Inserm), Hakan Ay(Harvard University), Traci M. Bartz(Mayo Clinic), Oscar R. Benavente(University of British Columbia), Steve Bevan(University Hospital Mútua de Terrassa), Giorgio B. Boncoraglio(George Washington University), Robert D. Brown(Mayo Clinic), Adam S. Butterworth(University of Cambridge), Caty Carrera(Universitat Autònoma de Barcelona), Cara L. Carty(Children's National), Daniel I. Chasman(Brigham and Women's Hospital), Wei-Min Chen(Washington University in St. Louis), John W. Cole(University of Maryland, Baltimore), Adolfo Correa(University of Mississippi Medical Center), Ioana Cotlarciuc(Royal Holloway University of London), Carlos Cruchaga(Uppsala University), John Danesh(University of North Carolina at Chapel Hill), Paul I. W. de Bakker(University of Basel), Anita L. DeStefano(Broad Institute), Marcel den Hoed(Uppsala University), Qing Duan(University of North Carolina at Chapel Hill), Stefan T. Engelter(University of Iceland), Guido J. Falcone(Broad Institute), Rebecca F. Gottesman(Johns Hopkins University), Raji P. Grewal(National Institutes of Health), Vilmundur Gudnason(Leeds General Infirmary), Stefan Gustafsson(Uppsala University), Jeffrey Haessler(University of Washington), Tamara B. Harris(National Institutes of Health), Ahamad Hassan(Leeds General Infirmary), Aki S. Havulinna(Finnish Institute for Health and Welfare), Susan R. Heckbert(Emory University), Elizabeth G. Holliday(Erasmus MC), George Howard(University of Alabama at Birmingham), Fang-Chi Hsu(University of Alabama at Birmingham), Hyacinth I. Hyacinth(Emory University), M. Arfan Ikram(Universitat Autònoma de Barcelona), Erik Ingelsson(Uppsala University), Marguerite R. Irvin(Leiden University Medical Center), Xueqiu Jian(Harvard University), Jordi Jiménez-Conde(Universitat Autònoma de Barcelona), Julie A. Johnson(University of Florida), J. Wouter Jukema(Leiden University Medical Center), Masahiro Kanai(Harvard University), Keith L. Keene(East Carolina University), Brett Kissela(University of Colorado Anschutz Medical Campus), Dawn Kleindorfer(University of Cincinnati Medical Center), Charles Kooperberg(University of Cambridge), Michiaki Kubo(National Institutes of Health), Leslie A. Lange(Washington University in St. Louis), Carl D. Langefeld(KU Leuven), Claudia Langenberg(Inserm), Lenore J. Launer(National Institutes of Health), Jin‐Moo Lee(Washington University in St. Louis), Robin Lemmens(Lund University), Didier Leys(Inserm), Cathryn M. Lewis(King's College London), Wei‐Yu Lin(University of Technology Sydney), Arne G. Lindgren(Lund University), Erik Lorentzen(University of Maryland, Baltimore), Patrik K. E. Magnusson(WinnMed), Jane Maguire(University of Technology Sydney), Ani Manichaikul(University of Mississippi Medical Center), Patrick F. McArdle(University of Maryland, Baltimore), James F. Meschia(Kyushu University), Braxton D. Mitchell(University of Maryland, Baltimore), Thomas H. Mosley(University of Washington), Michael A. Nalls(National Institutes of Health), Toshiharu Ninomiya(Kyushu University), Martin O’Donnell(University of Washington), Bruce M. Psaty(Brigham and Women's Hospital), Sara L. Pulit(University of Washington), Kristiina Rannikmäe(University of Virginia), Alex P. Reiner(Harvard University), Kathryn M. Rexrode(Brigham and Women's Hospital), Kenneth Rice(University of Washington), Stephen S. Rich(The Lundquist Institute), Paul M. Ridker(Brigham and Women's Hospital), Natalia S. Rost(Harvard University), Peter M. Rothwell(University of Oxford), Jerome I. Rotter(The Lundquist Institute), Tatjana Rundek(University of Miami), Ralph L. Sacco(University of Miami), Saori Sakaue(Medical University of Graz), Michèle M. Sale(Universitätsmedizin Greifswald), Veikko Salomaa(Universitätsmedizin Greifswald), Bishwa R. Sapkota(Royal Holloway University of London), Reinhold Schmidt(Jagiellonian University), Carsten Oliver Schmidt(Universitätsmedizin Greifswald), Ulf Schminke(Justus-Liebig-Universität Gießen), Pankaj Sharma(Royal Holloway University of London), Agnieszka Slowik(Jagiellonian University), Cathie Sudlow(The University of Melbourne), Christian Tanislav(deCODE Genetics (Iceland)), Turgut Tatlisumak(deCODE Genetics (Iceland)), Kent D. Taylor(The Lundquist Institute), Vincent Thijs(The University of Melbourne), Gudmar Thorleifsson(deCODE Genetics (Iceland)), U. Thorsteinsdottir(deCODE Genetics (Iceland)), Steffen Tiedt(LMU Klinikum), Stella Trompet(University of Cambridge), Christophe Tzourio(Albert Einstein College of Medicine), Cornelia M. van Duijn(Erasmus MC), Matthew Walters(University of Washington), Nicholas J. Wareham(Boston University), Sylvia Wassertheil-Smoller(Albert Einstein College of Medicine), James G. Wilson(Erasmus MC), Kerri L. Wiggins(University of Washington), Qiong Yang(Boston University), Salim Yusuf(Population Health Research Institute), Najaf Amin, Hugo J. Aparicio(Inserm), Donna K. Arnett(Harvard University), John Attia(Center for Research in Environmental Epidemiology), Alexa Beiser(University of Perugia), Claudine Berr(University of Maryland, Baltimore), Julie E. Buring, Mariana Bustamante, Valeria Caso(University Hospital Mútua de Terrassa), Yu‐Ching Cheng(Inserm), Seung Hoan Choi(Skåne University Hospital), Ayesha Chowhan(Universitat Autònoma de Barcelona), Natàlia Cullell(Universitätsmedizin Greifswald), Jean‐François Dartigues(Lund University), Hossein Delavaran(University of Glasgow), Pilar Delgado(Dayanand Medical College & Hospital), Marcus Dörr(Karolinska Institutet), Gunnar Engström(Washington University in St. Louis), Ian Ford(Tohoku Medical Megabank Organization), Wander S. Gurpreet(Washington University in St. Louis), Anders Hamsten(Skåne University Hospital), Laura Heitsch(Uppsala University), Atsushi Hozawa, Laura Ibáñez(The Ohio State University), Andreea Ilinca(University of Gothenburg), Martin Ingelsson(Finnish Institute for Health and Welfare), Motoki Iwasaki(Institut des Maladies Neurodégénératives), Rebecca D. Jackson(King's College London), Katarina Jood(Kyushu University), Pekka Jousilahti(Kyushu University), Sara Kaffashian(National University Hospital of Iceland), Lalit Kalra(Heidelberg University), Masahiro Kamouchi(Erasmus MC), Takanari Kitazono(Mútua Terrassa), Ólafur Kjartansson(Albert Einstein College of Medicine), Manja Kloß(University of Washington), Peter J. Koudstaal(John Hunter Hospital), Jerzy Krupiński(University of Oxford), Daniel Labovitz(Uppsala University), Cathy C. Laurie(Centre for Human Genetics), Christopher Levi, Linxin Li(Wake Forest University), Lars Lind(University of Pittsburgh), Cecilia M. Lindgren(BioBank Japan), Vasileios Lioutas(Helsinki University Hospital), Yong Mei Liu(BioBank Japan), Oscar L. Lopez(Tohoku Medical Megabank Organization), Makoto Hirata(Universitat Autònoma de Barcelona), Nicolas Martinez‐Majander(University of Liverpool), Koichi Matsuda(University Hospital Mútua de Terrassa), Naoko Minegishi(Helmholtz Zentrum München), Joan Montaner(Skåne University Hospital), Andrew P. Morris(Tohoku Medical Megabank Organization), Elena Muiño(Fondazione IRCCS Istituto Neurologico Carlo Besta), Martina Müller‐Nurasyid, Bo Norrving(Karolinska Institutet), Soichi Ogishima(Jagiellonian University), Eugenio Parati(Finnish Institute for Health and Welfare), Leema Reddy Peddareddygari(University of Brescia), Nancy L. Pedersen(Mario Negri Institute for Pharmacological Research), Joanna Pera(Universitat de Barcelona), Markus Perola(Universitat Autònoma de Barcelona), Alessandro Pezzini(Universitat Autònoma de Barcelona), Silvana Pileggi, Raquel Rabionet(Universitat Autònoma de Barcelona), Iolanda Riba‐Llena(King's College London), Marta Ribasés(Institute for Molecular Medicine Finland), José R. Romero(Dayanand Medical College & Hospital), Jaume Roquer, Anthony G. Rudd(Iwate Medical University), Antti-Pekka Sarin, Sarju Ralhan(Iwate Medical University), Chloé Sarnowski, Makoto Sasaki, Claudia L. Satizábal(Helsinki University Hospital), Mamoru Satoh(deCODE Genetics (Iceland)), Naveed Sattar(Icelandic Heart Association), Norie Sawada(Iwate Medical University), Gerli Sibolt(Hospital Del Mar), Ásgeir Sigurðsson(University of Gothenburg), Albert V. Smith(University of Maryland, Baltimore), Kenji Sobue(University of Glasgow), Carolina Soriano‐Tárraga(Helmholtz Zentrum München), Tara M. Stanne(Tohoku Medical Megabank Organization), O. Colin Stine(Aichi Cancer Center), David J. Stott(Iwate Medical University), Konstantin Strauch(Universitätsmedizin Greifswald), Takako Takai(Helsinki University Hospital), Hideo Tanaka(University Hospital Mútua de Terrassa), Kozo Tanno(Université de Caen Normandie), Alexander Teumer, Liisa Tomppo(Erasmus MC), Nuria P. Torres‐Aguila(Reykjavík University), Emmanuel Touzé(Erasmus MC), Shoichiro Tsugane(Universitätsmedizin Greifswald), André G. Uitterlinden(Aichi Cancer Center), Einar Már Valdimarsson(University of Michigan), Sven J. van der Lee(University of Virginia), Henry Völzke(King's College London), Kenji Wakai(University of Washington), David R. Weir(University of Maryland, Baltimore), Stephen R. Williams, Charles Wolfe(University of Oklahoma Health Sciences Center), Quenna Wong(Lund University), Huichun Xu(University of Gothenburg), Taiki Yamaji(Helsinki University Hospital), Dharambir K. Sanghera(Oklahoma City University), Olle Melander(Lund University), Christina Jern(University of Rostock), Daniel Strbian(University of Helsinki), Israel Fernández‐Cadenas(Universitat Autònoma de Barcelona), W. T. Longstreth(Broad Institute), Arndt Rolfs(Population Health Research Institute), Jun Hata(Kyushu University), Daniel Woo(University of Pennsylvania), Jonathan Rosand(Broad Institute), Guillaume Pare(Population Health Research Institute), Jemma C. Hopewell(University of Maryland, Baltimore), Danish Saleheen(The University of Texas at San Antonio Health Science Center), Kari Stefansson(deCODE Genetics (Iceland)), Bradford B. Worrall(Université de Bordeaux), Steven J. Kittner(University of Maryland, Baltimore), Sudha Seshadri(The University of Texas at San Antonio Health Science Center), Myriam Fornage(Institut des Maladies Neurodégénératives), Hugh S. Markus(Université de Bordeaux), Joanna M. M. Howson(University of Cambridge), Yoichiro Kamatani(Lund University), Stéphanie Debette(University of Cambridge), Martin Dichgans(Helsinki University Hospital), Dharambir K. Sanghera(Oklahoma City University), Olle Melander(Lund University), Christina Jern(University of Rostock), Daniel Strbian(University of Helsinki), Israel Fernández‐Cadenas(Universitat Autònoma de Barcelona), W. T. Longstreth(Broad Institute), Arndt Rolfs(Population Health Research Institute), Jun Hata(Kyushu University), Daniel Woo(University of Pennsylvania), Jonathan Rosand(Broad Institute), Guillaume Pare(Population Health Research Institute), Jemma C. Hopewell(University of Maryland, Baltimore), Danish Saleheen(The University of Texas at San Antonio Health Science Center), Kari Stefansson(deCODE Genetics (Iceland)), Bradford B. Worrall(Université de Bordeaux), Steven J. Kittner(University of Maryland, Baltimore), Sudha Seshadri(The University of Texas at San Antonio Health Science Center), Myriam Fornage(Institut des Maladies Neurodégénératives), Hugh S. Markus(Université de Bordeaux), Joanna M. M. Howson(University of Cambridge), Yoichiro Kamatani(Kyoto University), Stéphanie Debette(University of Cambridge), Martin Dichgans(German Center for Neurodegenerative Diseases)
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