Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

Aude Nicolas; Kevin P. Kenna; Alan E. Renton; Nicola Ticozzi; Faraz Faghri; Ruth Chia; Janice A. Dominov; Brendan Kenna; Mike A. Nalls; Pamela Keagle; Alberto Rivera; Wouter van Rheenen; Natalie A. Murphy; Joke J.F.A. van Vugt; Joshua T. Geiger; Rick A. A. van der Spek; Hannah A. Pliner; Shankaracharya; Bradley Smith; Giuseppe Marangi; Simon Topp; Yevgeniya Abramzon; Soragia Athina Gkazi; John D. Eicher; Aoife Kenna; Francesco O. Logullo; Isabella Laura Simone; Giancarlo Logroscino; Fabrizio Salvi; Ilaria Bartolomei; Giuseppe Borghero; Maria Rita Murru; Emanuela Costantino; Carla Pani; Roberta Puddu; Carla Caredda; Valeria Piras; Stefania Tranquilli; Stefania Cuccu; Daniela Corongiu; Maurizio Melis; Antonio Milia; Francesco Marrosu; Maria Giovanna Marrosu; Gianluca Floris; Antonino Cannas; Stefania Tranquilli; Margherita Capasso; Claudia Caponnetto; Gianluigi Mancardi; Paola Origone; Paola Mandich; F. L. Conforti; Sebastiano Cavallaro; Gabriele Mora; Kalliopi Marinou; Riccardo Sideri; Silvana Penco; Lorena Mosca; Christian Lunetta; Giuseppe Lauria Pinter; Massimo Corbo; Nilo Riva; Paola Carrera; Paolo Volanti; Jessica Mandrioli; Nicola Fini; Antonio Fasano; Lucio Tremolizzo; A Arosio; Carlo Ferrarese; Francesca Trojsi; Gioacchino Tedeschi; Maria Rosaria Monsurrò; Giovanni Piccirillo; Cinzia Femiano; Anna Ticca; Enzo Ortu; Vincenzo La Bella; Rossella Spataro; Tiziana Colletti; Mario Sabatelli; Marcella Zollino; Amelia Conte; Marco Luigetti; Serena Lattante; Giuseppe Marangi; Marialuisa Santarelli; Antonio Petrucci; Maura Pugliatti; Angelo Pirisi; Leslie D. Parish; Patrizia Occhineri; Fabio Giannini; Stefania Battistini; Claudia Ricci; Michele Benigni; Tea B. Cau; Daniela Loi; Andrea Calvo; Cristina Moglia; Maura Brunetti; Marco Barberis; Gabriella Restagno; Federico Casale; Giuseppe Marrali; Giuseppe Fuda; Irene Ossola; Stefania Cammarosano; Antonio Canosa; Antonio Ilardi; Umberto Manera; Maurizio Grassano; Raffaella Tanel; Fabrizio Pisano; Gabriele Mora; Andrea Calvo; Letizia Mazzini; Nilo Riva; Jessica Mandrioli; Claudia Caponnetto; Stefania Battistini; Paolo Volanti; Vincenzo La Bella; F. L. Conforti; Giuseppe Borghero; Sonia Messina; Isabella Laura Simone; Francesca Trojsi; Fabrizio Salvi; Francesco O. Logullo; Sandra D’Alfonso; Lucia Corrado; Margherita Capasso; Luigi Ferrucci; Matthew B. Harms; David B. Goldstein; Neil A. Shneider; Stephen A. Goutman; Zachary Simmons; Jonathan Mill; Siddharthan Chandran; Suvankar Pal; Georgios Manousakis; Stanley H. Appel; Ericka Simpson; Leo H. Wang; Robert H. Baloh; Summer Gibson; Richard Bedlack; David Lacomis; Dhruv Sareen; Alexander Sherman; Lucie Bruijn; Michelle A. Penny; Cristiane Araújo Martins Moreno; Sitharthan Kamalakaran; David B. Goldstein; Andrew S. Allen; Stanley H. Appel; Robert H. Baloh; Richard Bedlack; Braden Boone; Robert H. Brown; John P. Carulli; Alessandra Chesi; Wendy K. Chung; Elizabeth T. Cirulli; Gregory M. Cooper; Julien Couthouis; Kelly L. Williams; Patrick A. Dion; Summer Gibson; Aaron D. Gitler; Jonathan D. Glass; David B. Goldstein; Yujun Han; Matthew B. Harms; Tim Harris; Sebastian Hayes; Angela Jones; Jonathan Keebler; Brian J. Krueger; Brittany N. Lasseigne; Shawn Levy; Yifan Lu; Tom Maniatis; Diane McKenna-Yasek; Timothy M. Miller; R Myers; Slavé Petrovski; Stefan M. Pulst; Alya R. Raphael; John M. Ravits; Zhong Ren; Guy A. Rouleau; Peter C. Sapp; Neil A. Shneider; Ericka Simpson; Katherine B. Sims; John F. Staropoli; Lindsay L. Waite; Quanli Wang; Jack R. Wimbish; Winnie Xin; Aaron D. Gitler; Tim Harris; R Myers; Hemali Phatnani; Justin Kwan; Dhruv Sareen; James R. Broach; Zachary Simmons; Ximena Arcila-Londono; Edward B. Lee; Vivianna M. Van Deerlin; Neil A. Shneider; Ernest Fraenkel; Lyle W. Ostrow; Frank Baas; Noah Zaitlen; James D. Berry; Andrea Malaspina; Pietro Fratta; Gregory A. Cox; Leslie M. Thompson; Steven Finkbeiner; Efthimios Dardiotis; Jonathan Mill; Siddharthan Chandran; Suvankar Pal; Eran Hornstein; Daniel J. MacGowan; Terry Heiman‐Patterson; Molly Hammell; Nikolaos A. Patsopoulos; Josh Dubnau; Avindra Nath; Hemali Phatnani; Rajeeva Musunuri; Uday S. Evani; Avinash Abhyankar; Michael C. Zody; Julia Kaye; Steven Finkbeiner; Stacia K. Wyman; Alexander LeNail; Leandro de Araújo Lima; Ernest Fraenkel; Jeffrey D. Rothstein; Clive N. Svendsen; Leslie M. Thompson; Jenny Van Eyk; Nicholas J. Maragakis; James D. Berry; Jonathan D. Glass; Jonathan Mill; Stephen J. Kolb; Robert H. Baloh; Merit Cudkowicz; Emily G. Baxi; Julia Kaye; Steven Finkbeiner; Stacia K. Wyman; Alex Lenail; Leandro de Araújo Lima; Ernest Fraenkel; Clive N. Svendsen; Leslie M. Thompson; Jennifer E. Van Eyk; James D. Berry; Timothy M. Miller; Stephen J. Kolb; Merit Cudkowicz; Emily G. Baxi; Michael Benatar; J. Paul Taylor; Gang Wu; Evadnie Rampersaud; Joanne Wuu; Rosa Rademakers; Stephan Züchner; Rebecca Schüle; Jacob L. McCauley; Sumaira Hussain; Anne Cooley; Marielle Wallace; Christine Clayman; Richard J. Barohn; Jeffrey Statland; John Ravits; Andrea Swenson; Carlayne E. Jackson; Jaya Trivedi; Shaida Khan; Jonathan Katz; Liberty Jenkins; Ted M. Burns; Kelly Gwathmey; James B. Caress; Corey T. McMillan; Lauren Elman; Erik P. Pioro; Jeannine M. Heckmann; Yuen T. So; David Walk; Samuel Maiser; Jinghui Zhang; Michael Benatar; J. Paul Taylor; Evadnie Rampersaud; Gang Wu; Joanne Wuu; Vincenzo Silani; Nicola Ticozzi; Cinzia Gellera; Antonia Ratti; Franco Taroni; Giuseppe Lauria; Federico Verde; Isabella Fogh; Cinzia Tiloca; Giacomo P. Comi; Gianni Sorarú; Cristina Cereda; Sandra D’Alfonso; Lucia Corrado; Fabiola De Marchi; Stefania Corti; Mauro Ceroni; Letizia Mazzini; Gabriele Siciliano; Massimiliano Filosto; Maurizio Inghilleri; Silvia Peverelli; Claudia Colombrita; Barbara Poletti; Luca Maderna; Roberto Del Bo; Stella Gagliardi; Giorgia Querin; Cinzia Bertolin; Viviana Pensato; Barbara Castellotti; Giuseppe Lauria; Federico Verde; Isabella Fogh; Cinzia Tiloca; Giacomo P. Comi; Gianni Sorarú; Cristina Cereda; William Camu; Kevin Mouzat; Serge Lumbroso; Philippe Corcia; Vincent Meininger; Gérard Besson; Emmeline Lagrange; Pierre Clavelou; Nathalie Guy; Philippe Couratier; Patrick Vourc’h; Véronique Danel; E Bernard; Gwendal Le Masson; Philippe Corcia; Hannu Laaksovirta; Liisa Myllykangas; Lilja Jansson; Miko Valori; John Ealing; Hisham Hamdalla; Sara Rollinson; Stuart Pickering‐Brown; Richard W. Orrell; Katie Sidle; Andrea Malaspina; John Hardy; Andrew Singleton; Janel O. Johnson; Sampath Arepalli; Peter C. Sapp; Diane McKenna-Yasek; Meraida Polak; Seneshaw Asress; Safa Al‐Sarraj; Andrew King; Claire Troakes; Caroline Vance; Jacqueline de Belleroche; Frank Baas; Anneloor L.M.A. ten Asbroek; José Luís Muñoz-Blanco; Dena G. Hernandez; Jinhui Ding; J. Raphael Gibbs; Sonja W. Scholz; Mary Kay Floeter; Roy H. Campbell; Francesco Landi; Robert Bowser; Stefan M. Pulst; John M. Ravits; Daniel J. MacGowan; Janine Kirby; Erik P. Pioro; Roger Pamphlett; James R. Broach; Glenn S. Gerhard; Travis Dunckley; Christopher B. Brady; Neil W. Kowall; Juan C. Troncoso; Isabelle Le Ber; Kevin Mouzat; Serge Lumbroso; Terry Heiman‐Patterson; Freya Kamel; Ludo Van Den Bosch; Robert H. Baloh; Tim M. Strom; Thomas Meitinger; Aleksey Shatunov; Kristel R. van Eijk; Mamede de Carvalho; Maarten Kooyman; Bas Middelkoop; Matthieu Moisse; Russell L. McLaughlin; Michael A. van Es; Markus Weber; Khrista Boylan; Marka van Blitterswijk; Rosa Rademakers; Karen Morrison; A. Nazli Basak; Jesús S. Mora; Vivian E. Drory; Pamela J. Shaw; Martin R. Turner; Kevin Talbot; Orla Hardiman; Kelly L. Williams; Jennifer A. Fifita; Garth A. Nicholson; Ian P. Blair; Guy A. Rouleau; Jesús Esteban‐Pérez; Alberto García‐Redondo; Ammar Al-Chalabi; Ahmad Al Kheifat; Ammar Al-Chalabi; Peter M. Andersen; A. Nazli Basak; Ian P. Blair; Adriano Chiò; Johnathan Cooper‐Knock; Philippe Corcia; Philippe Couratier; Mamede de Carvalho; Annelot Dekker; Vivian E. Drory; Alberto García‐Redondo; Marc Gotkine; Orla Hardiman; Winston Hide; Alfredo Iacoangeli; Jonathan D. Glass; Kevin Kenna; Matthew C. Kiernan; Maarten Kooyman; John Landers; Russell L. McLaughlin; Bas Middelkoop; Jonathan Mill; Miguel Mitne‐Neto; Mattieu Moisse; Jesús Mora Pardina; Karen Morrison; Stephen Newhouse; Susana Pinto; Sara L. Pulit; Wim Robberecht; Aleksey Shatunov; Pamela Shaw; Christopher E. Shaw; Vincenzo Silani; William Sproviero; Gijs Tazelaar; Nicola Ticozzi; Michael A. van Es; Leonard van den Berg; Rick A. A. van der Spek; Kristel van Eijk; Michael A. van Es; Wouter van Rheenen; Joke J.F.A. van Vugt; Jan H. Veldink; Markus Weber; Kelly L. Williams; Mayana Zatz; Denis C. Bauer; Natalie A. Twine; Ekaterina Rogaeva; Lorne Zinman; Lyle W. Ostrow; Nicholas J. Maragakis; Jeffrey D. Rothstein; Zachary Simmons; Johnathan Cooper‐Knock; Alexis Brice; Stephen A. Goutman; Eva L. Feldman; Summer Gibson; Franco Taroni; Antonia Ratti; Cinzia Gellera; Michael A. van Es; Wim Robberecht; Pietro Fratta; Mario Sabatelli; Christian Lunetta; Albert C. Ludolph; Peter M. Andersen; Jochen H. Weishaupt; William Camu; John Q. Trojanowski; Vivianna M. Van Deerlin; Robert H. Brown; Leonard H. van den Berg; Jan H. Veldink; Matthew B. Harms; Jonathan D. Glass; David J. Stone; Pentti J. Tienari; Vincenzo Silani; Adriano Chiò; Christopher E. Shaw; Bryan J. Traynor; John E. Landers

doi:10.1016/j.neuron.2018.02.027

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

Aude Nicolas(National Institute on Aging), Kevin P. Kenna(University of Massachusetts Chan Medical School), Alan E. Renton(National Institute on Aging), Nicola Ticozzi(University of Milan), Faraz Faghri(University of Illinois Urbana-Champaign), Ruth Chia(National Institute on Aging), Janice A. Dominov(University of Massachusetts Chan Medical School), Brendan Kenna(University of Massachusetts Chan Medical School), Mike A. Nalls(Data Tecnica International (United States)), Pamela Keagle(University of Massachusetts Chan Medical School), Alberto Rivera(National Institute on Aging), Wouter van Rheenen(University Medical Center Utrecht), Natalie A. Murphy(National Institute on Aging), Joke J.F.A. van Vugt(University Medical Center Utrecht), Joshua T. Geiger(National Institute of Neurological Disorders and Stroke), Rick A. A. van der Spek(University Medical Center Utrecht), Hannah A. Pliner(National Institute on Aging), Shankaracharya(University of Massachusetts Chan Medical School), Bradley Smith(King's College London), Giuseppe Marangi(National Institute on Aging), Simon Topp(King's College London), Yevgeniya Abramzon(National Institute on Aging), Soragia Athina Gkazi(King's College London), John D. Eicher(Merck & Co., Inc., Rahway, NJ, USA (United States)), Aoife Kenna(University of Massachusetts Chan Medical School), Francesco O. Logullo(Marche Polytechnic University), Isabella Laura Simone(University of Turin), Giancarlo Logroscino(Università degli Studi del Piemonte Orientale “Amedeo Avogadro”), Fabrizio Salvi(San Raffaele University of Rome), Ilaria Bartolomei(Azienda Unita' Sanitaria Locale Di Modena), Giuseppe Borghero(University of Cagliari), Maria Rita Murru(University of Siena), Emanuela Costantino(Fondazione Salvatore Maugeri), Carla Pani(University of Palermo), Roberta Puddu(Institute of Neurological Sciences), Carla Caredda(University of Cagliari), Valeria Piras(University of Messina), Stefania Tranquilli(University of Bari Aldo Moro), Stefania Cuccu(University of Campania "Luigi Vanvitelli"), Daniela Corongiu, Maurizio Melis(Marche Polytechnic University), Antonio Milia(Università degli Studi del Piemonte Orientale “Amedeo Avogadro”), Francesco Marrosu(Università degli Studi del Piemonte Orientale “Amedeo Avogadro”), Maria Giovanna Marrosu(University of Chieti-Pescara), Gianluca Floris(National Institute on Aging), Antonino Cannas(Columbia University), Stefania Tranquilli(Columbia University), Margherita Capasso(University of Chieti-Pescara), Claudia Caponnetto(Ospedale Policlinico San Martino), Gianluigi Mancardi, Paola Origone(HudsonAlpha Institute for Biotechnology), Paola Mandich(New York Genome Center), F. L. Conforti(Institute of Neurological Sciences), Sebastiano Cavallaro(New York Genome Center), Gabriele Mora(Fondazione Salvatore Maugeri), Kalliopi Marinou(New York Genome Center), Riccardo Sideri(Gladstone Institutes), Silvana Penco(Gladstone Institutes), Lorena Mosca(Gladstone Institutes), Christian Lunetta(Centro Clinico Nemo), Giuseppe Lauria Pinter(Laboratoire de Biométrie et Biologie Evolutive), Massimo Corbo(Broad Institute), Nilo Riva(Cedars-Sinai Medical Center), Paola Carrera(University of California, Irvine), Paolo Volanti(Cedars-Sinai Medical Center), Jessica Mandrioli(Washington University in St. Louis), Nicola Fini(The Ohio State University Wexner Medical Center), Antonio Fasano(Harvard University), Lucio Tremolizzo(Johns Hopkins University), A Arosio(University of Miami), Carlo Ferrarese(St. Jude Children's Research Hospital), Francesca Trojsi(St. Jude Children's Research Hospital), Gioacchino Tedeschi(St. Jude Children's Research Hospital), Maria Rosaria Monsurrò(University of Miami), Giovanni Piccirillo(University of Milan), Cinzia Femiano(IRCCS Istituto Auxologico Italiano), Anna Ticca(King's College London), Enzo Ortu(IRCCS Istituto Auxologico Italiano), Vincenzo La Bella(Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico), Rossella Spataro(University of Padua), Tiziana Colletti(Center for Genomic Science), Mario Sabatelli(Centro Clinico Nemo), Marcella Zollino(University of Helsinki), Amelia Conte(University of Helsinki), Marco Luigetti(University of Helsinki), Serena Lattante(University of Helsinki), Giuseppe Marangi(Salford Royal NHS Foundation Trust), Marialuisa Santarelli(Salford Royal NHS Foundation Trust), Antonio Petrucci(University of Manchester), Maura Pugliatti(University of Manchester), Angelo Pirisi(University College London), Leslie D. Parish(National Hospital for Neurology and Neurosurgery), Patrizia Occhineri(Queen Mary University of London), Fabio Giannini(National Hospital for Neurology and Neurosurgery), Stefania Battistini(University of Siena), Claudia Ricci(National Institute on Aging), Michele Benigni(National Institute on Aging), Tea B. Cau(University of Massachusetts Chan Medical School), Daniela Loi(University of Massachusetts Chan Medical School), Andrea Calvo(Emory University), Cristina Moglia(Emory University), Maura Brunetti(King's College London), Marco Barberis(King's College London), Gabriella Restagno(King's College London), Federico Casale(King's College London), Giuseppe Marrali(Imperial College London), Giuseppe Fuda(Leiden University Medical Center), Irene Ossola(Amsterdam UMC Location University of Amsterdam), Stefania Cammarosano(Hospital General Universitario Gregorio Marañón), Antonio Canosa(National Institute on Aging), Antonio Ilardi(National Institute on Aging), Umberto Manera(National Institute on Aging), Maurizio Grassano(Johns Hopkins University), Raffaella Tanel(National Institute of Neurological Disorders and Stroke), Fabrizio Pisano(University of Illinois Urbana-Champaign), Gabriele Mora(Università Cattolica del Sacro Cuore), Andrea Calvo(Barrow Neurological Institute), Letizia Mazzini(Università degli Studi del Piemonte Orientale “Amedeo Avogadro”), Nilo Riva(San Raffaele University of Rome), Jessica Mandrioli(Mount Sinai Beth Israel), Claudia Caponnetto(Ospedale Policlinico San Martino), Stefania Battistini(University of Siena), Paolo Volanti(The University of Sydney), Vincenzo La Bella(Princeton University), F. L. Conforti(Institute of Neurological Sciences), Giuseppe Borghero(Translational Genomics Research Institute), Sonia Messina(Boston University), Isabella Laura Simone(Boston University), Francesca Trojsi(Johns Hopkins University), Fabrizio Salvi(Centre National de la Recherche Scientifique), Francesco O. Logullo(Marche Polytechnic University), Sandra D’Alfonso(Institute for Neurosciences of Montpellier), Lucia Corrado(Università degli Studi del Piemonte Orientale “Amedeo Avogadro”), Margherita Capasso(University of Chieti-Pescara), Luigi Ferrucci(National Institute on Aging), Matthew B. Harms(Cedars-Sinai Medical Center), David B. Goldstein(Helmholtz Zentrum München), Neil A. Shneider(Helmholtz Zentrum München), Stephen A. Goutman(King's College London), Zachary Simmons(University Medical Center Utrecht), Jonathan Mill(University of Lisbon), Siddharthan Chandran(SURFsara (Netherlands)), Suvankar Pal(University Medical Center Utrecht), Georgios Manousakis(VIB-KU Leuven Center for Brain & Disease Research), Stanley H. Appel(Trinity College Dublin), Ericka Simpson(University Medical Center Utrecht), Leo H. Wang(Kantonsspital St. Gallen), Robert H. Baloh(Cedars-Sinai Medical Center), Summer Gibson(University of Utah), Richard Bedlack(Jacksonville College), David Lacomis(University of Southampton), Dhruv Sareen(Boğaziçi University), Alexander Sherman(Hospital Universitario San Rafael), Lucie Bruijn(Tel Aviv Sourasky Medical Center), Michelle A. Penny(University of Sheffield), Cristiane Araújo Martins Moreno(University of Oxford), Sitharthan Kamalakaran(University of Oxford), David B. Goldstein(Trinity College Dublin), Andrew S. Allen(Macquarie University), Stanley H. Appel(Macquarie University), Robert H. Baloh(Cedars-Sinai Medical Center), Richard Bedlack(Macquarie University), Braden Boone(Montreal Neurological Institute and Hospital), Robert H. Brown(University of Massachusetts Chan Medical School), John P. Carulli(Research Institute Hospital 12 de Octubre), Alessandra Chesi(King's College London), Wendy K. Chung(University of Toronto), Elizabeth T. Cirulli(Sunnybrook Health Science Centre), Gregory M. Cooper(Johns Hopkins University), Julien Couthouis(Johns Hopkins University), Kelly L. Williams(Johns Hopkins University), Patrick A. Dion(Penn State Milton S. Hershey Medical Center), Summer Gibson(University of Utah), Aaron D. Gitler(Centre National de la Recherche Scientifique), Jonathan D. Glass(Emory University), David B. Goldstein(University of Michigan), Yujun Han(University of Utah), Matthew B. Harms(Fondazione IRCCS Istituto Neurologico Carlo Besta), Tim Harris(University of Milan), Sebastian Hayes(Fondazione IRCCS Istituto Neurologico Carlo Besta), Angela Jones(KU Leuven), Jonathan Keebler(KU Leuven), Brian J. Krueger(University College London), Brittany N. Lasseigne(Università Cattolica del Sacro Cuore), Shawn Levy(Centro Clinico Nemo), Yifan Lu(Universität Ulm), Tom Maniatis(Umeå University), Diane McKenna-Yasek(University of Massachusetts Chan Medical School), Timothy M. Miller(Washington University in St. Louis), R Myers(HudsonAlpha Institute for Biotechnology), Slavé Petrovski(University of Pennsylvania), Stefan M. Pulst(University of Massachusetts Chan Medical School), Alya R. Raphael(University Medical Center Utrecht), John M. Ravits(University Medical Center Utrecht), Zhong Ren(Columbia University), Guy A. Rouleau(Montreal Neurological Institute and Hospital), Peter C. Sapp(University of Massachusetts Chan Medical School), Neil A. Shneider(University of Helsinki), Ericka Simpson(University of Milan), Katherine B. Sims(University of Turin), John F. Staropoli(King's College London), Lindsay L. Waite(Johns Hopkins University), Quanli Wang(University of Massachusetts Chan Medical School), Jack R. Wimbish(Marche Polytechnic University), Winnie Xin(University of Bari Aldo Moro), Aaron D. Gitler(Stanford University), Tim Harris, R Myers(HudsonAlpha Institute for Biotechnology), Hemali Phatnani(University of Cagliari), Justin Kwan, Dhruv Sareen, James R. Broach(Penn State Milton S. Hershey Medical Center), Zachary Simmons(Penn State Milton S. Hershey Medical Center), Ximena Arcila-Londono, Edward B. Lee, Vivianna M. Van Deerlin(University of Siena), Neil A. Shneider(University of Siena), Ernest Fraenkel(Massachusetts Institute of Technology), Lyle W. Ostrow(Johns Hopkins University), Frank Baas(Leiden University Medical Center), Noah Zaitlen(Università Cattolica del Sacro Cuore), James D. Berry(Massachusetts General Hospital), Andrea Malaspina(Queen Mary University of London), Pietro Fratta(University College London), Gregory A. Cox(University of Siena), Leslie M. Thompson(University of California, Irvine), Steven Finkbeiner(Gladstone Institutes), Efthimios Dardiotis, Jonathan Mill(Washington University in St. Louis), Siddharthan Chandran, Suvankar Pal(Institute of Neurological Sciences), Eran Hornstein, Daniel J. MacGowan(Mount Sinai Beth Israel), Terry Heiman‐Patterson(Temple University), Molly Hammell, Nikolaos A. Patsopoulos, Josh Dubnau, Avindra Nath(Centro Clinico Nemo), Hemali Phatnani(University of Milan), Rajeeva Musunuri(New York Genome Center), Uday S. Evani(San Raffaele University of Rome), Avinash Abhyankar(New York Genome Center), Michael C. Zody(Fondazione Salvatore Maugeri), Julia Kaye(Gladstone Institutes), Steven Finkbeiner(Gladstone Institutes), Stacia K. Wyman(Gladstone Institutes), Alexander LeNail(Massachusetts Institute of Technology), Leandro de Araújo Lima(Gladstone Institutes), Ernest Fraenkel(Massachusetts Institute of Technology), Jeffrey D. Rothstein(Johns Hopkins University), Clive N. Svendsen(Cedars-Sinai Medical Center), Leslie M. Thompson(University of California, Irvine), Jenny Van Eyk(Cedars-Sinai Medical Center), Nicholas J. Maragakis(Johns Hopkins University), James D. Berry(Massachusetts General Hospital), Jonathan D. Glass(Emory University), Jonathan Mill(Washington University in St. Louis), Stephen J. Kolb(The Ohio State University Wexner Medical Center), Robert H. Baloh(Cedars-Sinai Medical Center), Merit Cudkowicz(Università Cattolica del Sacro Cuore), Emily G. Baxi(Johns Hopkins University), Julia Kaye(Gladstone Institutes), Steven Finkbeiner(Gladstone Institutes), Stacia K. Wyman(Gladstone Institutes), Alex Lenail(National Institute on Aging), Leandro de Araújo Lima(Gladstone Institutes), Ernest Fraenkel(Massachusetts Institute of Technology), Clive N. Svendsen(Cedars-Sinai Medical Center), Leslie M. Thompson(University of California, Irvine), Jennifer E. Van Eyk(Cedars-Sinai Medical Center), James D. Berry(Massachusetts General Hospital), Timothy M. Miller(Washington University in St. Louis), Stephen J. Kolb(University of Siena), Merit Cudkowicz(Massachusetts General Hospital), Emily G. Baxi(Johns Hopkins University), Michael Benatar(University of Miami), J. Paul Taylor(St. Jude Children's Research Hospital), Gang Wu(St. Jude Children's Research Hospital), Evadnie Rampersaud(St. Jude Children's Research Hospital), Joanne Wuu(University of Miami), Rosa Rademakers(Mayo Clinic in Florida), Stephan Züchner, Rebecca Schüle(IRCCS Istituto Auxologico Italiano), Jacob L. McCauley(University of Milan), Sumaira Hussain(University of Milan), Anne Cooley, Marielle Wallace(University of Siena), Christine Clayman, Richard J. Barohn, Jeffrey Statland, John Ravits(University of California San Diego), Andrea Swenson, Carlayne E. Jackson, Jaya Trivedi(Columbia University), Shaida Khan(Columbia University), Jonathan Katz(Boston University), Liberty Jenkins(University of Michigan), Ted M. Burns(Penn State Milton S. Hershey Medical Center), Kelly Gwathmey(Washington University in St. Louis), James B. Caress, Corey T. McMillan(National Institute on Aging), Lauren Elman, Erik P. Pioro(Cleveland Clinic), Jeannine M. Heckmann, Yuen T. So(University Medical Center Utrecht), David Walk(Cedars-Sinai Medical Center), Samuel Maiser(University of Utah), Jinghui Zhang(University College London), Michael Benatar(University of Miami), J. Paul Taylor(St. Jude Children's Research Hospital), Evadnie Rampersaud(St. Jude Children's Research Hospital), Gang Wu(St. Jude Children's Research Hospital), Joanne Wuu(University of Miami), Vincenzo Silani(IRCCS Istituto Auxologico Italiano), Nicola Ticozzi(IRCCS Istituto Auxologico Italiano), Cinzia Gellera(Cedars-Sinai Medical Center), Antonia Ratti(IRCCS Istituto Auxologico Italiano), Franco Taroni(Fondazione IRCCS Istituto Neurologico Carlo Besta), Giuseppe Lauria(University of Milan), Federico Verde(IRCCS Istituto Auxologico Italiano), Isabella Fogh(IRCCS Istituto Auxologico Italiano), Cinzia Tiloca(IRCCS Istituto Auxologico Italiano), Giacomo P. Comi(Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico), Gianni Sorarú(University of Padua), Cristina Cereda(Center for Genomic Science), Sandra D’Alfonso, Lucia Corrado(Università degli Studi del Piemonte Orientale “Amedeo Avogadro”), Fabiola De Marchi(University of Utah), Stefania Corti(Stanford University), Mauro Ceroni(Emory University), Letizia Mazzini(Università degli Studi del Piemonte Orientale “Amedeo Avogadro”), Gabriele Siciliano(Emory University), Massimiliano Filosto(Columbia University), Maurizio Inghilleri, Silvia Peverelli, Claudia Colombrita, Barbara Poletti(Emory University), Luca Maderna, Roberto Del Bo, Stella Gagliardi, Giorgia Querin(KU Leuven), Cinzia Bertolin(National Institute on Aging), Viviana Pensato(University of Massachusetts Chan Medical School), Barbara Castellotti(Washington University in St. Louis), Giuseppe Lauria(University of Milan), Federico Verde(IRCCS Istituto Auxologico Italiano), Isabella Fogh(University of Utah), Cinzia Tiloca(University of New Haven), Giacomo P. Comi(Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico), Gianni Sorarú(University of Padua), Cristina Cereda(Montreal Neurological Institute and Hospital), William Camu(University of Massachusetts Chan Medical School), Kevin Mouzat(Boston University), Serge Lumbroso(Université de Nîmes), Philippe Corcia(Université de Tours), Vincent Meininger, Gérard Besson, Emmeline Lagrange, Pierre Clavelou, Nathalie Guy, Philippe Couratier(New York Genome Center), Patrick Vourc’h, Véronique Danel, E Bernard(Princeton University), Gwendal Le Masson(Penn State Milton S. Hershey Medical Center), Philippe Corcia(Université de Tours), Hannu Laaksovirta(University of Helsinki), Liisa Myllykangas(University of Helsinki), Lilja Jansson(Boston University), Miko Valori(Broad Institute), John Ealing(Johns Hopkins University), Hisham Hamdalla(Leiden University Medical Center), Sara Rollinson(University of Manchester), Stuart Pickering‐Brown(University of Manchester), Richard W. Orrell(Queen Mary University of London), Katie Sidle(National Hospital for Neurology and Neurosurgery), Andrea Malaspina(Queen Mary University of London), John Hardy(University of California, Irvine), Andrew Singleton(Gladstone Institutes), Janel O. Johnson(National Institute on Aging), Sampath Arepalli(Washington University in St. Louis), Peter C. Sapp(University of Massachusetts Chan Medical School), Diane McKenna-Yasek(University of Massachusetts Chan Medical School), Meraida Polak(Emory University), Seneshaw Asress(Mount Sinai Beth Israel), Safa Al‐Sarraj(King's College London), Andrew King(King's College London), Claire Troakes(King's College London), Caroline Vance(King's College London), Jacqueline de Belleroche(Emory University), Frank Baas(Gladstone Institutes), Anneloor L.M.A. ten Asbroek(Gladstone Institutes), José Luís Muñoz-Blanco(Gladstone Institutes), Dena G. Hernandez(National Institute on Aging), Jinhui Ding(Gladstone Institutes), J. Raphael Gibbs(Broad Institute), Sonja W. Scholz(Johns Hopkins University), Mary Kay Floeter(Cedars-Sinai Medical Center), Roy H. Campbell(University of Illinois Urbana-Champaign), Francesco Landi(Università Cattolica del Sacro Cuore), Robert Bowser(Barrow Neurological Institute), Stefan M. Pulst(Harvard University), John M. Ravits(Emory University), Daniel J. MacGowan(Mount Sinai Beth Israel), Janine Kirby(The Ohio State University Wexner Medical Center), Erik P. Pioro(Cedars-Sinai Medical Center), Roger Pamphlett(The University of Sydney), James R. Broach(Johns Hopkins University), Glenn S. Gerhard(University of Miami), Travis Dunckley(Translational Genomics Research Institute), Christopher B. Brady(St. Jude Children's Research Hospital), Neil W. Kowall(Boston University), Juan C. Troncoso(Johns Hopkins University), Isabelle Le Ber(Centre National de la Recherche Scientifique), Kevin Mouzat(Université de Nîmes), Serge Lumbroso(Université de Nîmes), Terry Heiman‐Patterson(Temple University), Freya Kamel(National Institute of Environmental Health Sciences), Ludo Van Den Bosch(Amsterdam UMC Location University of Amsterdam), Robert H. Baloh(Cedars-Sinai Medical Center), Tim M. Strom(Helmholtz Zentrum München), Thomas Meitinger(Helmholtz Zentrum München), Aleksey Shatunov(Johns Hopkins University), Kristel R. van Eijk(University Medical Center Utrecht), Mamede de Carvalho(Queen Mary University of London), Maarten Kooyman(SURFsara (Netherlands)), Bas Middelkoop(University Medical Center Utrecht), Matthieu Moisse(VIB-KU Leuven Center for Brain & Disease Research), Russell L. McLaughlin(Emory University), Michael A. van Es(University Medical Center Utrecht), Markus Weber(Kantonsspital St. Gallen), Khrista Boylan(Mayo Clinic in Florida), Marka van Blitterswijk(Princeton University), Rosa Rademakers(Mayo Clinic in Florida), Karen Morrison(University of Southampton), A. Nazli Basak(Cleveland Clinic), Jesús S. Mora(Hospital Universitario San Rafael), Vivian E. Drory(University of Utah), Pamela J. Shaw(University of Sheffield), Martin R. Turner(University of Oxford), Kevin Talbot(University of Oxford), Orla Hardiman(University of Milan), Kelly L. Williams(University of Milan), Jennifer A. Fifita(Fondazione IRCCS Istituto Neurologico Carlo Besta), Garth A. Nicholson(University of Milan), Ian P. Blair(Fondazione IRCCS Istituto Neurologico Carlo Besta), Guy A. Rouleau(Montreal Neurological Institute and Hospital), Jesús Esteban‐Pérez(Research Institute Hospital 12 de Octubre), Alberto García‐Redondo(King's College London), Ammar Al-Chalabi(King's College London), Ahmad Al Kheifat(Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico), Ammar Al-Chalabi(University of Padua), Peter M. Andersen(Center for Genomic Science), A. Nazli Basak(Università degli Studi del Piemonte Orientale “Amedeo Avogadro”), Ian P. Blair(Università degli Studi del Piemonte Orientale “Amedeo Avogadro”), Adriano Chiò(Neuroscience Institute), Johnathan Cooper‐Knock(University of Siena), Philippe Corcia(Université de Tours), Philippe Couratier(Università degli Studi del Piemonte Orientale “Amedeo Avogadro”), Mamede de Carvalho(Fondazione Salvatore Maugeri), Annelot Dekker, Vivian E. Drory(Tel Aviv Sourasky Medical Center), Alberto García‐Redondo, Marc Gotkine(Ospedale Policlinico San Martino), Orla Hardiman(Trinity College Dublin), Winston Hide, Alfredo Iacoangeli, Jonathan D. Glass(Emory University), Kevin Kenna(University of Massachusetts Chan Medical School), Matthew C. Kiernan(Fondazione IRCCS Istituto Neurologico Carlo Besta), Maarten Kooyman(SURFsara (Netherlands)), John Landers(University of Massachusetts Chan Medical School), Russell L. McLaughlin(Université de Montpellier), Bas Middelkoop(University Medical Center Utrecht), Jonathan Mill(Centre Hospitalier Universitaire de Nîmes), Miguel Mitne‐Neto, Mattieu Moisse(VIB-KU Leuven Center for Brain & Disease Research), Jesús Mora Pardina, Karen Morrison(University of Southampton), Stephen Newhouse, Susana Pinto(Montreal Neurological Institute and Hospital), Sara L. Pulit, Wim Robberecht(VIB-KU Leuven Center for Brain & Disease Research), Aleksey Shatunov(King's College London), Pamela Shaw(University of Sheffield), Christopher E. Shaw(King's College London), Vincenzo Silani(IRCCS Istituto Auxologico Italiano), William Sproviero, Gijs Tazelaar(Umeå University), Nicola Ticozzi(IRCCS Istituto Auxologico Italiano), Michael A. van Es(VIB-KU Leuven Center for Brain & Disease Research), Leonard van den Berg(University Medical Center Utrecht), Rick A. A. van der Spek(University Medical Center Utrecht), Kristel van Eijk(University Medical Center Utrecht), Michael A. van Es(University Medical Center Utrecht), Wouter van Rheenen(University of Lisbon), Joke J.F.A. van Vugt(University Medical Center Utrecht), Jan H. Veldink(Tel Aviv Sourasky Medical Center), Markus Weber(Kantonsspital St. Gallen), Kelly L. Williams(Macquarie University), Mayana Zatz(Trinity College Dublin), Denis C. Bauer, Natalie A. Twine, Ekaterina Rogaeva(Emory University), Lorne Zinman(Sunnybrook Health Science Centre), Lyle W. Ostrow(Johns Hopkins University), Nicholas J. Maragakis(Johns Hopkins University), Jeffrey D. Rothstein(Johns Hopkins University), Zachary Simmons(Trinity College Dublin), Johnathan Cooper‐Knock(University Medical Center Utrecht), Alexis Brice(Centre National de la Recherche Scientifique), Stephen A. Goutman(University of Michigan), Eva L. Feldman(University of Michigan), Summer Gibson(University of Utah), Franco Taroni(Fondazione IRCCS Istituto Neurologico Carlo Besta), Antonia Ratti(University of Michigan), Cinzia Gellera(Fondazione IRCCS Istituto Neurologico Carlo Besta), Michael A. van Es(Jacksonville College), Wim Robberecht(VIB-KU Leuven Center for Brain & Disease Research), Pietro Fratta(King's College London), Mario Sabatelli(Centro Clinico Nemo), Christian Lunetta(King's College London), Albert C. Ludolph(University of Milan), Peter M. Andersen(Université de Montpellier), Jochen H. Weishaupt(Universität Ulm), William Camu(University of Milan), John Q. Trojanowski(VIB-KU Leuven Center for Brain & Disease Research), Vivianna M. Van Deerlin(University Medical Center Utrecht), Robert H. Brown(University of Massachusetts Chan Medical School), Leonard H. van den Berg(University Medical Center Utrecht), Jan H. Veldink(University Medical Center Utrecht), Matthew B. Harms(University Medical Center Utrecht), Jonathan D. Glass(Emory University), David J. Stone(University Medical Center Utrecht), Pentti J. Tienari(University of Helsinki), Vincenzo Silani(IRCCS Istituto Auxologico Italiano), Adriano Chiò(Neuroscience Institute), Christopher E. Shaw(King's College London), Bryan J. Traynor(National Institute on Aging), John E. Landers(University of Massachusetts Chan Medical School)

Neuron

March 1, 2018

10.1016/j.neuron.2018.02.027

Cited by 715Open Access

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