Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets

CAMCAP Study Group; David C. Wedge; Gunes Gundem; Thomas J. Mitchell; Dan J. Woodcock; Iñigo Martincorena; Mohammed Ghori; Jorge Zamora; Adam P. Butler; Hayley C. Whitaker; Zsofia Kote‐Jarai; Ludmil B. Alexandrov; Peter Van Loo; Charlie E. Massie; Stefan C. Dentro; Anne Y. Warren; Clare Verrill; Daniel M. Berney; Nening M. Dennis; Sue Merson; Steve Hawkins; William Howat; Yong‐Jie Lu; Adam Lambert; Jonathan Kay; Bárbara Kremeyer; Katalin Karászi; Hayley J. Luxton; Niedzica Camacho; Luke Marsden; Sandra E. Edwards; Lucy Matthews; Valeria Bo; Daniel Leongamornlert; Stuart McLaren; Chi‐Fai Ng; Yongwei Yu; Hongwei Zhang; Tokhir Dadaev; Sarah Thomas; Douglas F. Easton; Mahbubl Ahmed; Elizabeth Bancroft; Cyril Fisher; Naomi Livni; David Nicol; Simon Tavaré; Pelvender Gill; Christopher Greenman; Vincent Khoo; Nicholas van As; Pardeep Kumar; Christopher Ogden; Declan Cahill; Alan Thompson; Erik Mayer; Edward Rowe; Tim Dudderidge; Vincent J. Gnanapragasam; Nimish Shah; Keiran Raine; David Jones; Andrew Menzies; Lucy Stebbings; Jon W. Teague; Steven Hazell; Cathy Corbishley; Johann S. de Bono; Gerhardt Attard; William B. Isaacs; Tapio Visakorpi; Michael Fraser; Paul C. Boutros; Robert G. Bristow; Paul Workman; Chris Sander; Freddie C. Hamdy; P. Andrew Futreal; Ultan McDermott; Bissan Al‐Lazikani; Andy G. Lynch; G. Steven Bova; Christopher S. Foster; Daniel S. Brewer; David E. Neal; Colin S. Cooper; Rosalind A. Eeles

doi:10.1038/s41588-018-0086-z

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets

CAMCAP Study Group(Open Data Institute), David C. Wedge(Wellcome Sanger Institute), Gunes Gundem(Memorial Sloan Kettering Cancer Center), Thomas J. Mitchell(Wellcome Sanger Institute), Dan J. Woodcock(Wellcome Sanger Institute), Iñigo Martincorena(Wellcome Sanger Institute), Mohammed Ghori(Wellcome Sanger Institute), Jorge Zamora(Wellcome Sanger Institute), Adam P. Butler(Wellcome Sanger Institute), Hayley C. Whitaker(Institute of Cancer Research), Zsofia Kote‐Jarai(Institute of Cancer Research), Ludmil B. Alexandrov(Wellcome Sanger Institute), Peter Van Loo(The Francis Crick Institute), Charlie E. Massie(University of Cambridge), Stefan C. Dentro(The Francis Crick Institute), Anne Y. Warren(Cambridge University Hospitals NHS Foundation Trust), Clare Verrill(Queen Mary University of London), Daniel M. Berney(Royal Marsden NHS Foundation Trust), Nening M. Dennis(Royal Marsden NHS Foundation Trust), Sue Merson(Institute of Cancer Research), Steve Hawkins(Cambridge University Hospitals NHS Foundation Trust), William Howat(Queen Mary University of London), Yong‐Jie Lu(Queen Mary University of London), Adam Lambert(University of Oxford), Jonathan Kay(Wellcome Sanger Institute), Bárbara Kremeyer(Wellcome Sanger Institute), Katalin Karászi(University of Oxford), Hayley J. Luxton(Memorial Sloan Kettering Cancer Center), Niedzica Camacho(Memorial Sloan Kettering Cancer Center), Luke Marsden(Institute of Cancer Research), Sandra E. Edwards(Institute of Cancer Research), Lucy Matthews(Cancer Research UK), Valeria Bo(Institute of Cancer Research), Daniel Leongamornlert(Institute of Cancer Research), Stuart McLaren(Chinese University of Hong Kong), Chi‐Fai Ng(Chinese University of Hong Kong), Yongwei Yu(Second Military Medical University), Hongwei Zhang(Institute of Cancer Research), Tokhir Dadaev(Royal Marsden NHS Foundation Trust), Sarah Thomas(Royal Marsden NHS Foundation Trust), Douglas F. Easton(Institute of Cancer Research), Mahbubl Ahmed(Institute of Cancer Research), Elizabeth Bancroft(Royal Marsden NHS Foundation Trust), Cyril Fisher(Royal Marsden NHS Foundation Trust), Naomi Livni(Royal Marsden NHS Foundation Trust), David Nicol(Royal Marsden NHS Foundation Trust), Simon Tavaré(Cancer Research UK), Pelvender Gill(University of East Anglia), Christopher Greenman(University of East Anglia), Vincent Khoo(Royal Marsden NHS Foundation Trust), Nicholas van As(Royal Marsden NHS Foundation Trust), Pardeep Kumar(Royal Marsden NHS Foundation Trust), Christopher Ogden(Royal Marsden NHS Foundation Trust), Declan Cahill(Royal Marsden NHS Foundation Trust), Alan Thompson(Royal Marsden NHS Foundation Trust), Erik Mayer(Royal Marsden NHS Foundation Trust), Edward Rowe(Royal Marsden NHS Foundation Trust), Tim Dudderidge(Royal Marsden NHS Foundation Trust), Vincent J. Gnanapragasam(University of Cambridge), Nimish Shah(Wellcome Sanger Institute), Keiran Raine(Wellcome Sanger Institute), David Jones(Wellcome Sanger Institute), Andrew Menzies(Wellcome Sanger Institute), Lucy Stebbings(Wellcome Sanger Institute), Jon W. Teague(Royal Marsden NHS Foundation Trust), Steven Hazell(Royal Marsden NHS Foundation Trust), Cathy Corbishley(Institute of Cancer Research), Johann S. de Bono(Institute of Cancer Research), Gerhardt Attard(Institute of Cancer Research), William B. Isaacs(Johns Hopkins University), Tapio Visakorpi(University Health Network), Michael Fraser(Ontario Institute for Cancer Research), Paul C. Boutros(Ontario Institute for Cancer Research), Robert G. Bristow(University Health Network), Paul Workman(Harvard University), Chris Sander(Harvard University), Freddie C. Hamdy(Wellcome Sanger Institute), P. Andrew Futreal(Wellcome Sanger Institute), Ultan McDermott(Institute of Cancer Research), Bissan Al‐Lazikani(Institute of Cancer Research), Andy G. Lynch(Johns Hopkins University), G. Steven Bova(Johns Hopkins University), Christopher S. Foster(University of East Anglia), Daniel S. Brewer(University of East Anglia), David E. Neal(University of East Anglia), Colin S. Cooper(University of East Anglia), Rosalind A. Eeles(Royal Marsden NHS Foundation Trust)

Nature Genetics

April 13, 2018

10.1038/s41588-018-0086-z

Cited by 237Open Access

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