Stricturing Crohn’s disease-like colitis in a patient treated with belatacept
Anne Bozon(Université de Montpellier), Guillaume Jeantet(Université de Montpellier), Benjamin Rivière(Université de Montpellier), Natalie Funakoshi(Université de Montpellier), Gaspard Dufour(Université de Montpellier), R Combes(Université de Montpellier), Jean-Christophe Valats(Université de Montpellier), Sylvie Delmas(Université de Montpellier), Jean Emmanuel Serre(Université de Montpellier), Michaël Bismuth(Université de Montpellier), José Ramos(Université de Montpellier), Moglie Le Quintrec(Université de Montpellier), Pierre Blanc(Université de Montpellier), Guillaume Pineton de Chambrun(Université de Montpellier)
Cited by 7Open Access
Abstract
Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) modifying agents have been involved in the development of intestinal inflammation, especially therapeutic monoclonal antibodies directed against CTLA-4. Here we report the appearance of a severe stricturing Crohn's disease-like colitis in a patient with a kidney allograft who was treated with belatacept, a recombinant CTLA-4-Ig fusion protein.
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