Persistence of Ebola Virus in Ocular Fluid during Convalescence

Jay B. Varkey(Office of Infectious Diseases), Jessica G. Shantha, Ian Crozier(Mulago Hospital), Colleen S. Kraft(Office of Infectious Diseases), G. Marshall Lyon(Office of Infectious Diseases), Aneesh K. Mehta(Office of Infectious Diseases), Gokul Kumar, Justine R. Smith(Flinders University), Markus H. Kainulainen, Shannon Whitmer, Ute Ströher, Timothy M. Uyeki, Bruce S. Ribner(Office of Infectious Diseases), Steven Yeh
New England Journal of Medicine
May 7, 2015
Cited by 468Open Access
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Abstract

Among the survivors of Ebola virus disease (EVD), complications that include uveitis can develop during convalescence, although the incidence and pathogenesis of EVD-associated uveitis are unknown. We describe a patient who recovered from EVD and was subsequently found to have severe unilateral uveitis during convalescence. Viable Zaire ebolavirus (EBOV) was detected in aqueous humor 14 weeks after the onset of EVD and 9 weeks after the clearance of viremia.


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