The MetaCyc database of metabolic pathways and enzymes

Ron Caspi(SRI International), Richard Billington(SRI International), Carol A. Fulcher(SRI International), Ingrid M. Keseler(SRI International), Anamika Kothari(SRI International), Markus Krummenacker(SRI International), Mario Latendresse(SRI International), Peter Midford(SRI International), Quang Ong(SRI International), Wai Kit Ong(SRI International), Suzanne Paley(SRI International), Pallavi Subhraveti(SRI International), Peter D. Karp(SRI International)
Nucleic Acids Research
October 2, 2017
10.1093/nar/gkx935
Cited by 930Open Access
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Abstract

MetaCyc (https://MetaCyc.org) is a comprehensive reference database of metabolic pathways and enzymes from all domains of life. It contains more than 2570 pathways derived from >54 000 publications, making it the largest curated collection of metabolic pathways. The data in MetaCyc is strictly evidence-based and richly curated, resulting in an encyclopedic reference tool for metabolism. MetaCyc is also used as a knowledge base for generating thousands of organism-specific Pathway/Genome Databases (PGDBs), which are available in the BioCyc (https://BioCyc.org) and other PGDB collections. This article provides an update on the developments in MetaCyc during the past two years, including the expansion of data and addition of new features.

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