CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer’s PSEN2 N141I neurons
Maitane Ortiz‐Virumbrales(Icahn School of Medicine at Mount Sinai), Sam Gandy(Nathan Kline Institute for Psychiatric Research)
Cited by 169
Related Papers
Estrogen regulates metabolism of Alzheimer amyloid beta precursor protein.
|Journal of Biological Chemistry|1994|368
Diabetes-Associated SorCS1 Regulates Alzheimer's Amyloid-β Metabolism: Evidence for Involvement of SorL1 and the Retromer Complex
|Journal of Neuroscience|2010|188
Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer’s disease
|Nature Communications|2022|109
Group II Metabotropic Glutamate Receptor Stimulation Triggers Production and Release of Alzheimer's Amyloid β<sub>42</sub>from Isolated Intact Nerve Terminals
|Journal of Neuroscience|2010|85
iPSC-derived familial Alzheimer’s PSEN2 N141I cholinergic neurons exhibit mutation-dependent molecular pathology corrected by insulin signaling
|Molecular Neurodegeneration|2018|55