NK cell recovery after haploidentical HSCT with posttransplant cyclophosphamide: dynamics and clinical implications
Antonio Russo, Giacomo Oliveira(Istituti di Ricovero e Cura a Carattere Scientifico), Sofia Berglund(Johns Hopkins University), Raffaella Greco, Valentina Gambacorta, Nicoletta Cieri(Istituti di Ricovero e Cura a Carattere Scientifico), Cristina Toffalori, Laura Zito, Francesca Lorentino, Simona Piemontese, Mara Morelli, Fabio Giglio, Andrea Assanelli, Maria Teresa Lupo Stanghellini, Chiara Bonini(Vita-Salute San Raffaele University), Jacopo Peccatori, Fabio Ciceri(Vita-Salute San Raffaele University), Leo Luznik(Johns Hopkins University), Luca Vago
Cited by 204Open Access
Abstract
Key Points Posttransplantation cyclophosphamide eliminates most mature donor NK cells infused with the graft, including alloreactive NK cells. High levels of serum interleukin-15 early after HSCT provide a favorable environment for adoptive infusion of mature donor NK cells.
Related Papers
No related papers found
Powered by citation graph analysis