TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics

Ian R. Mackenzie; Alexandra M. Nicholson; Mohona Sarkar; James Messing; Maria D. Purice; Cyril Pottier; Kavya Annu; Matt Baker; Ralph B. Perkerson; Aishe Kurti; Billie J. Matchett; Tanja Mittag; Jamshid Temirov; Ging‐Yuek Robin Hsiung; Charles Krieger; Melissa E. Murray; Masato Kato; John Denis Fryer; Leonard Petrucelli; Lorne Zinman; Sandra Weıntraub; Marsel Mesulam; Julia Keith; Sasha Živković; Veronica Hirsch‐Reinshagen; Raymond P. Roos; Stephan Züchner; Neill R. Graff‐Radford; Ronald C. Petersen; Richard J. Caselli; Zbigniew K. Wszołek; Elizabeth Finger; Carol F. Lippa; David Lacomis; Heather Stewart; Dennis W. Dickson; Hong Joo Kim; Ekaterina Rogaeva; Eileen H. Bigio; Khrista Boylan; J. Paul Taylor; Rosa Rademakers

doi:10.1016/j.neuron.2017.07.025

TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics

Ian R. Mackenzie(Vancouver Coastal Health), Alexandra M. Nicholson(Jacksonville College), Mohona Sarkar(St. Jude Children's Research Hospital), James Messing(St. Jude Children's Research Hospital), Maria D. Purice(St. Jude Children's Research Hospital), Cyril Pottier(Jacksonville College), Kavya Annu(St. Jude Children's Research Hospital), Matt Baker(Jacksonville College), Ralph B. Perkerson(Jacksonville College), Aishe Kurti(Jacksonville College), Billie J. Matchett(Jacksonville College), Tanja Mittag(St. Jude Children's Research Hospital), Jamshid Temirov(St. Jude Children's Research Hospital), Ging‐Yuek Robin Hsiung(Vancouver Coastal Health), Charles Krieger(Vancouver Coastal Health), Melissa E. Murray(Jacksonville College), Masato Kato(The University of Texas Southwestern Medical Center), John Denis Fryer(Jacksonville College), Leonard Petrucelli(Jacksonville College), Lorne Zinman(Sunnybrook Health Science Centre), Sandra Weıntraub(Northwestern University), Marsel Mesulam(Northwestern University), Julia Keith(Sunnybrook Health Science Centre), Sasha Živković(University of Pittsburgh), Veronica Hirsch‐Reinshagen(Vancouver Coastal Health), Raymond P. Roos(University of Chicago), Stephan Züchner(University of Miami), Neill R. Graff‐Radford(Jacksonville College), Ronald C. Petersen(Mayo Clinic), Richard J. Caselli(Mayo Clinic in Arizona), Zbigniew K. Wszołek(Jacksonville College), Elizabeth Finger(Western University), Carol F. Lippa(Thomas Jefferson University), David Lacomis(University of Pittsburgh), Heather Stewart(Vancouver Coastal Health), Dennis W. Dickson(Jacksonville College), Hong Joo Kim(St. Jude Children's Research Hospital), Ekaterina Rogaeva(University of Toronto), Eileen H. Bigio(Northwestern University), Khrista Boylan(Jacksonville College), J. Paul Taylor(St. Jude Children's Research Hospital), Rosa Rademakers(Jacksonville College)

Neuron

August 1, 2017

10.1016/j.neuron.2017.07.025

Cited by 646Open Access

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