The regulation of immune tolerance by FOXP3Ling Lu(Nanjing Medical University), Joseph Barbi(Roswell Park Comprehensive Cancer Center), Fan Pan(Sidney Kimmel Comprehensive Cancer Center)Nature reviews. ImmunologyJuly 31, 201710.1038/nri.2017.75Cited by 570Open AccessFull TextSaveCiteExport RISWatch citationsAbstractRelated PapersThe immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3Craig L. Bennett, Jacinda R. Christie, Fred Ramsdell et al.|Nature Genetics|2001|3.3kDisruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouseMary E. Brunkow, Eric W. Jeffery, Kathryn A. Hjerrild et al.|Nature Genetics|2001|2.6kT Cell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell DevelopmentNaganari Ohkura, Masahide Hamaguchi, Hiromasa Morikawa et al.|Immunity|2012|737Epigenetic Regulation of Foxp3 Expression in Regulatory T Cells by DNA MethylationGirdhari Lal, Nan Zhang, William van der Touw et al.|The Journal of Immunology|2009|550Foxp3 Exploits a Pre-Existent Enhancer Landscape for Regulatory T Cell Lineage SpecificationRobert Samstein, Aaron Arvey, Steven Z. Josefowicz et al.|Cell|2012|477