Preference of Arabidopsis thaliana GH3.5 acyl amido synthetase for growth versus defense hormone acyl substrates is dictated by concentration of amino acid substrate aspartate

Rebecca Mackelprang(University of California, Berkeley), Rachel A. Okrent(University of California, Berkeley), Mary C. Wildermuth(University of California, Berkeley)
Phytochemistry
July 22, 2017
Cited by 28Open Access
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Abstract

for IAA. Therefore, GH3.5 catalyzed formation of SA-Asp would occur, fine-tuning localized defensive responses through conversion of active free SA to SA-Asp. Taken together, we show how GH3.5, with dual activity on IAA and SA, can integrate cellular metabolic status via Asp to provide fine control of growth vs. defense outcomes and hormone homeostasis.


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