The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity
Jacquelyn A. Gorman(Seattle Children's Hospital), David J. Rawlings(Center for Infectious Disease Research), Mohamed Oukka(University of Washington), John S. Errett(University of Washington), Jane H. Buckner(Benaroya Research Institute), Christian Hundhausen(Benaroya Research Institute), Courtnee Clough(Cincinnati Children's Hospital Medical Center), Michael Gale(University of Washington), Eric J. Allenspach(University of Washington), Amy E.L. Stone(University of Colorado Denver), Richard G. James(Center for Infectious Disease Research), Karen Cerosaletti(Virginia Mason Medical Center), Daniel B. Stetson(University of Washington), Yan Ge(Tongji University), Socheath Khim(Seattle Children's Hospital), Patrick Concannon(University of Florida), Denny Liggitt(University of Washington), Tanvi Arkatkar(Fred Hutch Cancer Center), Xuezhi Dai(China Pharmaceutical University), Kathleen Pestal(University of California, Berkeley)
Cited by 139
Related Papers
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
|The Journal of Experimental Medicine|2007|2.4k
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers
|Nature Genetics|2015|744
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis
|Nature Genetics|2012|677