Bioorthogonal double-fluorogenic siliconrhodamine probes for intracellular super-resolution microscopy

Eszter Kozma(Hungarian Academy of Sciences), Gemma Estrada Girona(European Molecular Biology Laboratory), Giulia Paci(European Molecular Biology Laboratory), Edward A. Lemke(European Molecular Biology Laboratory), Péter Kele(Hungarian Academy of Sciences)
Chemical Communications
January 1, 2017
Cited by 93Open Access
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Abstract

A series of double-fluorogenic siliconrhodamine probes were synthesized. These tetrazine-functionalized, membrane-permeable labels allowed site-specific bioorthogonal tagging of genetically manipulated intracellular proteins and subsequent imaging using super-resolution microscopy.


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