Cerebellar patients do not benefit from cerebellar or M1 transcranial direct current stimulation during force-field reaching adaptation

Thomas Hulst(Essen University Hospital), Liane John(Essen University Hospital), Michael Küper(Essen University Hospital), Jos N. van der Geest(Erasmus MC), Sophia Göricke(Essen University Hospital), Opher Donchin(Ben-Gurion University of the Negev), Dagmar Timmann(Essen University Hospital)
Journal of Neurophysiology
May 3, 2017
Cited by 47Open Access
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Abstract

Transcranial direct current stimulation (tDCS) has been identified as a potential tool in the rehabilitation of cerebellar disease. We investigated whether tDCS of the cerebellum and primary motor cortex could alleviate motor impairments of subjects with cerebellar degeneration. The present study did not find stimulation effects of tDCS in young controls, aging controls, and individuals with cerebellar degeneration during reach adaptation. Our results require a re-evaluation of the clinical potential of tDCS in cerebellar patients.


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