An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function
Daniel Matějů(Friedrich Miescher Institute), Simon Alberti(Center for Systems Biology Dresden)
Cited by 478
Related Papers
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
|Cell|2015|3.2k
Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau Phase
|Cell Reports|2017|410
Granulostasis: Protein Quality Control of RNP Granules
|Frontiers in Molecular Neuroscience|2017|164
Small molecule modulation of a redox-sensitive stress granule protein dissolves stress granules with beneficial outcomes for familial amyotrophic lateral sclerosis models
|bioRxiv (Cold Spring Harbor Laboratory)|2019|91
Small-molecule dissolution of stress granules by redox modulation benefits ALS models
|Nature Chemical Biology|2025|37