Human Demographic History Impacts Genetic Risk Prediction across Diverse Populations

Alicia R. Martin(Broad Institute), Christopher R. Gignoux(Stanford University), Raymond K. Walters(Broad Institute), Genevieve L. Wojcik(Stanford University), Benjamin M. Neale(Broad Institute), Simon Gravel(McGill Genome Centre), Mark J. Daly(Broad Institute), Carlos D. Bustamante(Stanford University), Eimear E. Kenny(Icahn School of Medicine at Mount Sinai)
The American Journal of Human Genetics
March 30, 2017
10.1016/j.ajhg.2017.03.004
Cited by 1,558Open Access
Full Text

Abstract

Related Papers

Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010
Harvey Whiteford, Louisa Degenhardt, Jürgen Rehm et al.|The Lancet|2013|6.1k
Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes
Jacob A. Tennessen, Abigail W. Bigham, Timothy D. O’Connor et al.|Science|2012|1.7k
Power and Predictive Accuracy of Polygenic Risk Scores
Frank Dudbridge|PLoS Genetics|2013|1.6k
New approaches to population stratification in genome-wide association studies
Alkes L. Price, Noah Zaitlen, David Reich et al.|Nature Reviews Genetics|2010|1.3k
The UK10K project identifies rare variants in health and disease
Writing group, Klaudia Walter, Josine L. Min et al.|Nature|2015|1.2k