IgA-coated <i>E. coli</i> enriched in Crohn’s disease spondyloarthritis promote T <sub>H</sub> 17-dependent inflammation

Monica Viladomiu(Cornell University), Charles Kivolowitz(Cornell University), Ahmed Abdulhamid(Cornell University), Belgin Dogan(Cornell University), Daniel Victorio(Cornell University), Jim G. Castellanos(Cornell University), Viola Woo(Cornell University), Fei Teng(University of Arizona), Nhan L. Tran(University of Arizona), Andrew Sczesnak(University of California, Berkeley), Christina L. L. Chai(Cornell University), Myunghoo Kim(Baylor College of Medicine), Gretchen E. Diehl(Baylor College of Medicine), Nadim J. Ajami(Baylor College of Medicine), Joseph F. Petrosino(Baylor College of Medicine), Xi Kathy Zhou(Cornell University), Sergio Schwartzman(Hospital for Special Surgery), Lisa A. Mandl(Hospital for Special Surgery), Meira Abramowitz(Cornell University), Vinita Jacob(Cornell University), Brian P. Bosworth(New York University), Adam F. Steinlauf(Cornell University), Ellen Scherl(Cornell University), Hsin-Jung Wu(University of Arizona), Kenneth W. Simpson(Cornell University), Randy Longman(Cornell University)
Science Translational Medicine
February 8, 2017
Cited by 314Open Access
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Abstract

17-dependent inflammation and offer microbial and immunophenotype stratification of CD-SpA that may guide medical and biologic therapy.


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