Impact of a High-fat Diet on Tissue Acyl-CoA and Histone Acetylation Levels
Alessandro Carrer(Cancer Research Institute of the Slovak Academy of Sciences), Joshua L.D. Parris(Cancer Research Institute of the Slovak Academy of Sciences), Sophie Trefely(Cancer Research Institute of the Slovak Academy of Sciences), Ryan A. Henry(Fox Chase Cancer Center), David C. Montgomery(National Institutes of Health), AnnMarie Torres(Cancer Research Institute of the Slovak Academy of Sciences), John M. Viola(Cancer Research Institute of the Slovak Academy of Sciences), Yin‐Ming Kuo(Fox Chase Cancer Center), Ian A. Blair(Translational Therapeutics (United States)), Jordan L. Meier(National Institutes of Health), Andrew J. Andrews(Fox Chase Cancer Center), Nathaniel W. Snyder(Drexel University), Kathryn E. Wellen(Cancer Research Institute of the Slovak Academy of Sciences)
Cited by 158Open Access
Abstract
This study thus provides evidence that diet can impact tissue acyl-CoA and histone acetylation levels and that acetyl-CoA abundance correlates with acetylation of specific histone lysines in WAT but not in the liver.
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