Silver-catalysed tandem hydroamination and cyclization of 2-trifluoromethyl-1,3-enynes with primary amines: modular entry to 4-trifluoromethyl-3-pyrrolines

Xiaofan Zhou(Green Chemistry), Chaoqian Huang(Green Chemistry), Yu Zeng(Green Chemistry), Jiarui Xiong(Green Chemistry), Yuanjing Xiao(Green Chemistry), Junliang Zhang(Green Chemistry)
Chemical Communications
December 19, 2016
Cited by 70

Abstract

as a catalyst under mild reaction conditions. This new method is compatible with alkyl, aryl, and allyl primary amines, representing an atom-economical protocol for the construction of 4-trifluoromethyl-3-pyrrolines for the first time.


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