441. Direct Comparison of EF1α and PGK Promoters Reveals Superior Performance of the PGK Promoter for Expression of the Common Gamma Chain in a Canine Model of In Vivo Foamy Virus Gene Therapy for Severe Combined Immunodeficiency
Christopher R. Burtner(Fred Hutch Cancer Center), Hans‐Peter Kiem(Fred Hutch Cancer Center), Daniel Humphrys(University of Washington), Jennifer E. Adair(University of Massachusetts Chan Medical School), Olivier Humbert(Fred Hutch Cancer Center), Andrew M. Scharenberg(CTI BioPharma (Italy)), Troy R. Torgerson(Allen Institute for Immunology), Nicholas Hubbard(University of Washington), Peter J. Felsburg(University of Pennsylvania), Grant D. Trobridge(Washington State University Spokane), Patricia O’Donnell(University of Pennsylvania), David J. Rawlings(Center for Infectious Disease Research)
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